Evidence map›Paper›PMID 28848720›Full record

ArticleFrontiers in cellular and infection microbiology2017

Pathogenic Leptospires Modulate Protein Expression and Post-translational Modifications in Response to Mammalian Host Signals.

Jarlath E Nally, Andre A Grassmann, Sébastien Planchon, Kjell Sergeant, Jenny Renaut, Janakiram Seshu, Alan J McBride, Melissa J Caimano

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  5. Evidence for a Putative Regulatory System Consisting of an ECF σInternational journal of molecular sciences · 2025
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  11. The Arsenal ofAntioxidants (Basel, Switzerland) · 2023
    Review
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  19. Review
  20. The sigma factor σMolecular microbiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Jarlath E NallyInfectious Bacterial Diseases Research, National Animal Disease Center, United States Department of Agriculture, Agricultural Research ServiceAmes, IA, United States.
Andre A GrassmannBiotechnology Unit, Technological Development Center, Federal University of PelotasPelotas, Brazil.
Sébastien PlanchonEnvironmental Research and Innovation Department, Luxembourg Institute of Science and TechnologyBelvaux, Luxembourg.
Kjell SergeantEnvironmental Research and Innovation Department, Luxembourg Institute of Science and TechnologyBelvaux, Luxembourg.
Jenny RenautEnvironmental Research and Innovation Department, Luxembourg Institute of Science and TechnologyBelvaux, Luxembourg.
Janakiram SeshuDepartment of Biology, University of Texas San AntoniaSan Antonia, TX, United States.
Alan J McBrideBiotechnology Unit, Technological Development Center, Federal University of PelotasPelotas, Brazil.
Melissa J CaimanoDepartments of Medicine, Pediatrics, and Molecular Biology and Biophysics, University of Connecticut Health CenterFarmington, CT, United States.
Luxembourg Institute of Science and Technology · LUMinistério da Saúde · BRUConn Health · USUnited States Department of Agriculture · USUniversidade Federal de Pelotas · BR

Funding

RpoS Regulation of Borrelia burgdorferi Genes in vivoR01AI029735 · NIAID · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI CAIMANO, MELISSA J, RADOLF, JUSTIN D · 1990 to 2022
$10.7M
RpoS Regulation of Borrelia burgdorferi Genes in vivoR56AI029735 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI RADOLF, JUSTIN D · 2012 to 2012
$536k
Identification of genes required by Leptospira interrogans for mammalian host adaptation and/or persistence in the rat modelR21AI128379 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CAIMANO, MELISSA J · 2017 to 2018
$439k
NIAID NIH HHS R01 AI029735NIAID NIH HHS R21 AI128379NIAID NIH HHS R56 AI029735
6 · The paper itself

Abstract

Pathogenic species of

Indexed as

Host-Parasite InteractionsProtein Processing, Post-TranslationalAnimalsAntigens, BacterialBacterial Outer Membrane ProteinsBacterial ProteinsDisease Models, AnimalDisease ReservoirsFemaleHumansLeptospira interrogansLeptospirosisLipoproteinsLysineProteomeRatsAntigens, BacterialBacterial Outer Membrane ProteinsBacterial ProteinsLipL32 protein, LeptospiraLipL41 protein, Leptospira interrogansLipoproteinsLysineProteomeDIGELeptospirapost-translational modificationsproteomicsspirochetes

Identifiers

PMID28848720
PMCPMC5553009
OpenAlexW2742652125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.