Evidence map›Paper›PMID 28848344›Full record

ArticleInternational journal of nanomedicine2017

Three-dimensional structure micelles of heparin-poloxamer improve the therapeutic effect of 17β-estradiol on endometrial regeneration for intrauterine adhesions in a rat model.

Si-Si Zhang, Wei-Ting Xia, Jie Xu, He-Lin Xu, Cui-Tao Lu, Ying-Zheng Zhao, Xue-Qing Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Si-Si ZhangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
Wei-Ting XiaDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
Jie XuSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang, People's Republic of China.
He-Lin XuSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang, People's Republic of China.
Cui-Tao LuSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang, People's Republic of China.
Ying-Zheng ZhaoSchool of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang, People's Republic of China.
Xue-Qing WuDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
First Affiliated Hospital of Wenzhou Medical University · CNWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrauterine adhesions (IUA) frequently occur after infectious or mechanical injury to the endometrium, which may lead to infertility and/or pregnancy complications. There are few effective treatments due to the complex function of endometrium and shortage of native materials. 17β-estradiol (E

Indexed as

AnimalsDisease Models, AnimalDrug Delivery SystemsEndometriumEstradiolFemaleHeparinHumansHydrogel, Polyethylene Glycol DimethacrylateMiceMicellesPhosphatidylinositol 3-KinasesPoloxamerPregnancyRats, Sprague-DawleyRegenerationEstradiolHeparinHydrogel, Polyethylene Glycol DimethacrylateMicellesPhosphatidylinositol 3-KinasesPoloxamer17β-estradiolendometrium regenerationendoplasmic reticulum stressheparin-poloxamer hydrogelintrauterine adhesions

Identifiers

PMID28848344
PMCPMC5557621
OpenAlexW2743933331

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.