Evidence map›Paper›PMID 28848324›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2017

The Prospective Health Assessment of Cataract Patients' Ocular Surface (PHACO) study: the effect of dry eye.

William B Trattler, Parag A Majmudar, Eric D Donnenfeld, Marguerite B McDonald, Karl G Stonecipher, Damien F Goldberg

Registry-linked trialAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04812951 (Cyclosporine 0.1% Eye Drops as Prophylactic Treatment in Post Surgical Ocular Surface System Failure Within The Age), which is not on this map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04812951 early_phase1completednot on this mapstarted 2021, after this paper: background citation

Cyclosporine 0.1% Eye Drops as Prophylactic Treatment in Post Surgical Ocular Surface System Failure Within The Age

TypeinterventionalSponsorCampus Bio-Medico UniversityRan2021 to 2022Enrolled101ConditionsOcular Surface Disease, Ocular InflammationArmsCycloSPORINE Ophthalmic 0.1% Ophthalmic Emulsion, cationorm eye drops
3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it.

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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William B TrattlerCenter for Excellence in Eye Care, Miami, FL, USA.
Parag A MajmudarChicago Cornea Consultants, Chicago, IL, USA.
Eric D DonnenfeldOphthalmic Consultants of Long Island, Garden City, NY, USA.
Marguerite B McDonaldOphthalmic Consultants of Long Island, Lynbrook, NY, USA.
Karl G StonecipherUniversity North Carolina School of Medicine, Chapel Hill, NC, USA.
Damien F GoldbergWolstan & Goldberg Eye Associates, Torrance, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the incidence and severity of dry eye as determined by the International Task Force (ITF) scale in patients being screened for cataract surgery. PATIENTS AND

methodsThis was a prospective, multi-center, observational study of 136 patients, at least 55 years of age, who were scheduled to undergo cataract surgery. The primary outcome measure was the incidence of dry eye as evaluated by grade on the ITF scale and secondary outcome measures include tear break-up time (TBUT), ocular surface disease index score, corneal staining with fluorescein, conjunctival staining with lissamine green, and a patient questionnaire to evaluate symptoms of dry eye.

resultsMean patient age was 70.7 years. A total of 73.5% of patients were Caucasian and 50% were female. Almost 60% had never complained of a foreign body sensation; only 13% complained of a foreign body sensation half or most of the time. The majority of patients (62.9%) had a TBUT ≤5 seconds, 77% of eyes had positive corneal staining and 50% of the eyes had positive central corneal staining. Eighteen percent had Schirmer's score with anesthesia ≤5 mm.

conclusionThe incidence of dry eye in patients scheduled to undergo cataract surgery in a real-world setting is higher than anticipated.

Indexed as

cataract surgery screeningdry eyeInternational Task Force scaleobservational study

Identifiers

PMID28848324
PMCPMC5557104

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Registered trials

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