Evidence map›Paper›PMID 28848228›Full record

ArticleNature microbiology2017

Efficient invasion by Toxoplasma depends on the subversion of host protein networks.

Amandine Guérin, Rosa Milagros Corrales, Michele L Parker, Mauld H Lamarque, Damien Jacot, Hiba El Hajj, Dominique Soldati-Favre, Martin J Boulanger, Maryse Lebrun

Abstract read
PubMed Publisher
In one paragraph

Article in Nature microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
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  8. Article
  9. Review
  10. Article
  11. Review
  12. Invasion ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Unravelling the sexual developmental biology ofFrontiers in cellular and infection microbiology · 2023
    Article
  14. Animal venoms: a novel source of anti-Frontiers in pharmacology · 2023
    Review
  15. mSphere · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Amandine GuérinUnité Mixte de Recherche 5235, Centre National de la Recherche Scientifique, Université de Montpellier 2, 34095, Montpellier, France.
Rosa Milagros CorralesUnité Mixte de Recherche 5235, Centre National de la Recherche Scientifique, Université de Montpellier 2, 34095, Montpellier, France.
Michele L ParkerDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada.
Mauld H LamarqueUnité Mixte de Recherche 5235, Centre National de la Recherche Scientifique, Université de Montpellier 2, 34095, Montpellier, France.
Damien JacotDepartment of Microbiology and Molecular Medicine, Centre Médical Universitaire, University of Geneva, 1 Rue Michel-Servet, 1206, Geneva, Switzerland.
Hiba El HajjDepartment of Internal Medicine and Experimental Pathology, Immunology and Microbiology, American University of Beirut, Beirut, 1107 2020, Lebanon.
Dominique Soldati-FavreDepartment of Microbiology and Molecular Medicine, Centre Médical Universitaire, University of Geneva, 1 Rue Michel-Servet, 1206, Geneva, Switzerland.
Martin J BoulangerDepartment of Biochemistry and Microbiology, University of Victoria, Victoria, BC, V8P 5C2, Canada.
Maryse LebrunUnité Mixte de Recherche 5235, Centre National de la Recherche Scientifique, Université de Montpellier 2, 34095, Montpellier, France. mylebrun@univ-montp2.fr.ORCID http://orcid.org/0000-0002-0962-0156
Université de Montpellier · FRUniversity of Geneva · CHUniversity of Victoria · CAAmerican University of Beirut · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apicomplexan parasites are important pathogens of humans and domestic animals, including Plasmodium species (the agents of malaria) and Toxoplasma gondii, which is responsible for toxoplasmosis. They replicate within the cells of their animal hosts, to which they gain access using a unique parasite-driven invasion process. At the core of the invasion machine is a structure at the interface between the invading parasite and host cell called the moving junction (MJ)

Indexed as

Adaptor Proteins, Signal TransducingAnimalsCalcium-Binding ProteinsCell Cycle ProteinsCells, CulturedCytoskeletal ProteinsDisease Models, AnimalDNA-Binding ProteinsEndosomal Sorting Complexes Required for TransportFemaleGene ExpressionGenetic VectorsHeLa CellsHost-Parasite InteractionsHumansMiceAdaptor Proteins, Signal TransducingCalcium-Binding ProteinsCD2-associated proteinCell Cycle ProteinsCytoskeletal ProteinsDNA-Binding ProteinsEndosomal Sorting Complexes Required for TransportPDCD6IP protein, humanProtozoan ProteinsRecombinant Proteinsrhoptry neck protein 2, Toxoplasma gondiiRON4 protein, Toxoplasma gondiiSH3KBP1 protein, humanTranscription FactorsTsg101 Protein

Identifiers

PMID28848228
OpenAlexW2747992208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.