Evidence map›Paper›PMID 28848064›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4

Kaitlin A Read, Michael D Powell, Chandra E Baker, Bharath K Sreekumar, Veronica M Ringel-Scaia, Holly Bachus, R Emily Martin, Ian D Cooley, Irving C Allen, Andre Ballesteros-Tato and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. AIOLOS-Associated Inborn Errors of Immunity.Journal of clinical immunology · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Aiolos represses CD4Nature communications · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Exploring the mechanism of berberine-mediated TPhytomedicine : international journal of phytotherapy and phytopharmacology · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Kaitlin A ReadVirginia Tech Carilion Research Institute, Roanoke, VA 24016.
Michael D PowellVirginia Tech Carilion Research Institute, Roanoke, VA 24016.
Chandra E BakerVirginia Tech Carilion Research Institute, Roanoke, VA 24016.
Bharath K SreekumarVirginia Tech Carilion Research Institute, Roanoke, VA 24016.
Veronica M Ringel-ScaiaGraduate Program in Translational Biology, Medicine, and Health, Virginia Tech, Blacksburg, VA 24061.ORCID 0000-0002-7318-4096
Holly BachusDivision of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294; and.ORCID 0000-0003-4368-1734
R Emily MartinVirginia Tech Carilion Research Institute, Roanoke, VA 24016.
Ian D CooleyVirginia Tech Carilion Research Institute, Roanoke, VA 24016.
Irving C AllenDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061.ORCID 0000-0001-9573-5250
Andre Ballesteros-TatoDivision of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294; and.
Kenneth J OestreichVirginia Tech Carilion Research Institute, Roanoke, VA 24016; oestrk@vtc.vt.edu.ORCID 0000-0002-3004-072X
Carilion Clinic · USVirginia–Maryland College of Veterinary Medicine · USUniversity of Alabama at Birmingham · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
Regulation of T-cell dependent B cell responses to influenzaR01AI110480 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BALLESTEROS-TATO, ANDRE · 2015 to 2019
$1.8M
Regulation of T helper cell differentiation by integrated STAT and Ikaros zinc finger transcription factor mechanismsR56AI127800 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI OESTREICH, KENNETH JOSEPH · 2017 to 2017
$263k
Evaluating NLR Modulation of Canonical and Non-Canonical NF-kB Signaling in IBDR03DK105975 · NIDDK · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI ALLEN, IRVING C · 2015 to 2016
$161k
NCI NIH HHS P30 CA013148NIAID NIH HHS R01 AI110480NIAID NIH HHS R56 AI127800NIDDK NIH HHS R03 DK105975
6 · The paper itself

Abstract

B cell lymphoma-6 (Bcl-6) is a transcriptional repressor that is required for the differentiation of T follicular helper (T

Indexed as

AnimalsCD4-Positive T-LymphocytesCell DifferentiationGene Expression RegulationIkaros Transcription FactorMiceOrthomyxoviridae InfectionsPromoter Regions, GeneticProto-Oncogene Proteins c-bcl-6STAT3 Transcription FactorT-Lymphocytes, Helper-InducerTrans-ActivatorsIkaros Transcription FactorIkzf3 protein, mouseProto-Oncogene Proteins c-bcl-6Stat3 protein, mouseSTAT3 Transcription FactorTrans-ActivatorsZfpn1a1 protein, mouse

Identifiers

PMID28848064
PMCPMC5657606
OpenAlexW2751860950

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.