Evidence map›Paper›PMID 28848007›Full record

ArticleAntimicrobial agents and chemotherapy2017

Potentiation of Tobramycin by Silver Nanoparticles against Pseudomonas aeruginosa Biofilms.

Marc B Habash, Mara C Goodyear, Amber J Park, Matthew D Surette, Emily C Vis, Robert J Harris, Cezar M Khursigara

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Metal Nanoparticles in Infection and Immunity.Immunological investigations · 2020
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Mapping the knowledge landscape ofFrontiers in cellular and infection microbiology · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Metals to combat antimicrobial resistance.Nature reviews. Chemistry · 2023
    Review
  14. Tryptone-stabilized silver nanoparticles' potential to mitigate planktonic and biofilm growth forms of Serratia marcescens.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marc B HabashSchool of Environmental Sciences, University of Guelph, Guelph, ON, Canada mhabash@uoguelph.ca ckhursig@uoguelph.ca.
Mara C GoodyearDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Amber J ParkDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Matthew D SuretteDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Emily C VisDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Robert J HarrisMolecular and Cellular Imaging Facility, University of Guelph, Guelph, ON, Canada.
Cezar M KhursigaraDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada mhabash@uoguelph.ca ckhursig@uoguelph.ca.ORCID 0000-0001-9263-7604
University of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing antibiotic resistance among pathogenic bacterial species is a serious public health problem and has prompted research examining the antibacterial effects of alternative compounds and novel treatment strategies. Compounding this problem is the ability of many pathogenic bacteria to form biofilms during chronic infections. Importantly, these communities are often recalcitrant to antibiotic treatments that show effectiveness against acute infection. The antimicrobial properties of silver have been known for decades, but recently silver and silver-containing compounds have seen renewed interest as antimicrobial agents for treating bacterial infections. The goal of this study was to assess the ability of citrate-capped silver nanoparticles (AgNPs) of various sizes, alone and in combination with the aminoglycoside antibiotic tobramycin, to inhibit established

Indexed as

Metal NanoparticlesAnti-Bacterial AgentsBiofilmsDrug SynergismHumansMicrobial Sensitivity TestsPseudomonas aeruginosaSilverTobramycinAnti-Bacterial AgentsSilverTobramycinbiofilmsPseudomonas aeruginosasilversynergy

Identifiers

PMID28848007
PMCPMC5655055
OpenAlexW2746950805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.