Evidence map›Paper›PMID 28847915›Full record

ArticleJournal of the American Heart Association2017

Arterial Stiffness Is Associated With Cytomegalovirus-Specific Senescent CD8

Hee Tae Yu, Jong-Chan Youn, Jong Hoon Kim, Yeon-Jae Seong, Su-Hyung Park, Hyeon Chang Kim, Won-Woo Lee, Sungha Park, Eui-Cheol Shin

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 48 citations in OpenAlex.

  1. Current issues in molecular biology · 2026
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  5. Observational
  6. The role of T cells in vascular aging, hypertension, and atherosclerosis.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  7. Article
  8. Review
  9. CD8American journal of physiology. Regulatory, integrative and comparative physiology · 2024
    Article
  10. Article
  11. The relationship betweenNorthern clinics of Istanbul · 2024
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Characteristics, outcomes, and predictors ofFrontiers in cardiovascular medicine · 2022
    Article
  19. Immunosenescence: an unexplored role in glomerulonephritis.Clinical & translational immunology · 2022
    Review
  20. Accumulation of CD28Biomolecules · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Hee Tae YuLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Korea.
Jong-Chan YounLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Korea.
Jong Hoon KimLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Korea.
Yeon-Jae SeongLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Korea.
Su-Hyung ParkLaboratory of Translational Immunology and Vaccinology, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Korea.
Hyeon Chang KimDepartment of Preventive Medicine, Cardiovascular and Metabolic Diseases Etiology Research Center, Yonsei University College of Medicine, Seoul, Korea.
Won-Woo LeeDepartment of Microbiology and Immunology and Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
Sungha ParkDivision of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea ecshin@kaist.ac.kr shpark0530@yuhs.ac.
Eui-Cheol ShinLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Korea ecshin@kaist.ac.kr shpark0530@yuhs.ac.
Korea Advanced Institute of Science and Technology · KRHallym University Dongtan Sacred Heart Hospital · KRSeoul National University · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArterial stiffness is a well-known predictor of future cardiovascular events. Search for the underlying mechanism of arterial stiffening is still under way. We investigated the relationship between arterial stiffness and cytomegalovirus infection in terms of T-cell senescence. METHODS AND

resultsArterial stiffness was evaluated using pulse wave velocity measurements in 415 Koreans (age 59±12 years). We also investigated the frequency of CD57

conclusionsWe demonstrate that arterial stiffness is associated with senescent CD57

Indexed as

ImmunosenescenceVascular StiffnessAdultAgedAged, 80 and overCD57 AntigensCD8-Positive T-LymphocytesCells, CulturedCell SeparationCytomegalovirusCytomegalovirus InfectionsFemaleFlow CytometryHost-Pathogen InteractionsHumansLinear ModelsCD57 Antigenscytomegalovirus matrix protein 65kDaPhosphoproteinsViral Matrix Proteinsarterial stiffnesscytomegalovirusimmunosenescencepulse wave velocityT cells

Identifiers

PMID28847915
PMCPMC5634298
OpenAlexW2747870555

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.