ArticleBiochemical and biophysical research communications2017
The L530R variation associated with recurrent kidney stones impairs the structure and function of TRPV5.
Article in Biochemical and biophysical research communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 24 citations in OpenAlex.
- Perspectives on TRPV Channels in the Structural and Computational Revolution Era.Advances in experimental medicine and biology · 2026Review
- A successful conclusion to the long search for TRPV5 pathogenic variants in monogenic hypercalciuria.European journal of human genetics : EJHG · 2024Article
- Decreased calcium permeability caused by biallelic TRPV5 mutation leads to autosomal recessive renal calcium-wasting hypercalciuria.European journal of human genetics : EJHG · 2024Article
- Structural mechanism of TRPV5 inhibition by econazole.Structure (London, England : 1993) · 2024Article
- Targeting TRP channels: recent advances in structure, ligand binding, and molecular mechanisms.Frontiers in molecular neuroscience · 2023Review
- Review
- Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.Cell reports · 2022Article
- Calcium selective channel TRPV6: Structure, function, and implications in health and disease.Gene · 2022Review
- The newest TRP channelopathy: Gain of function TRPM3 mutations cause epilepsy and intellectual disability.Channels (Austin, Tex.) · 2021Review
- Genetics of kidney stone disease.Nature reviews. Urology · 2020Review
- High-resolution structures of transient receptor potential vanilloid channels: Unveiling a functionally diverse group of ion channels.Protein science : a publication of the Protein Society · 2020Review
- Modeling the structural and dynamical changes of the epithelial calcium channel TRPV5 caused by the A563T variation based on the structure of TRPV6.Journal of biomolecular structure & dynamics · 2019Article
- Article
- Genetics of common complex kidney stone disease: insights from genome-wide association studies.Urolithiasis · 2019Review
- Molecular insights into the structural and dynamical changes of calcium channel TRPV6 induced by its interaction with phosphatidylinositol 4,5-bisphosphate.Journal of biomolecular structure & dynamicsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
TRPV5 is a Ca
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.