Evidence map›Paper›PMID 28847562›Full record

ReviewPharmacology & therapeutics2018

Cannabis use during pregnancy: Pharmacokinetics and effects on child development.

Kimberly S Grant, Rebekah Petroff, Nina Isoherranen, Nephi Stella, Thomas M Burbacher

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pharmacology & therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

130 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  11. The psychoactive cannabinoid THC inhibits peripheral nociceptors by targeting NaNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kimberly S GrantDepartment of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, USA; Center on Human Development and Disability, University of Washington, Seattle, WA, USA; Washington National Primate Research Center, University of Washington, Seattle, WA, USA. Electronic address: ksg@uw.edu.
Rebekah PetroffDepartment of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, USA.
Nina IsoherranenDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA.
Nephi StellaDepartment of Pharmacology, School of Medicine, University of Washington, Seattle, WA, USA; Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle, WA, USA.
Thomas M BurbacherDepartment of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, USA; Center on Human Development and Disability, University of Washington, Seattle, WA, USA; Washington National Primate Research Center, University of Washington, Seattle, WA, USA.

Funding

Washington National Primate Research CenterP51OD010425 · OD · UNIVERSITY OF WASHINGTON · PI Mari Ostendorf · 2012 to 2026
$201.8M
Understanding Fetal Exposure to Cannabinoids Through In Vitro and In Vivo StudiesP01DA032507 · NIDA · UNIVERSITY OF WASHINGTON · PI UNADKAT, JASHVANT D · 2013 to 2023
$12.4M
Intellectual and Developmental Disabilities Research CenterU54HD083091 · NICHD · UNIVERSITY OF WASHINGTON · PI GURALNICK, MICHAEL J · 2014 to 2019
$7.9M
Cannabinoid Signaling System in Microglial CellsR01DA014486 · NIDA · UNIVERSITY OF WASHINGTON · PI STELLA, NEPHI · 2001 to 2016
$4.2M
Role of ABHD6 in 2-AG SignalingR01DA026430 · NIDA · UNIVERSITY OF WASHINGTON · PI STELLA, NEPHI · 2009 to 2018
$3.4M
Anti-Epileptic Action of ABHD6 Inhibitors as Treatment for Dravet SyndromeR21NS098777 · NINDS · UNIVERSITY OF WASHINGTON · PI STELLA, NEPHI · 2017 to 2018
$427k
NICHD NIH HHS U54 HD083091NIDA NIH HHS P01 DA032507NIDA NIH HHS R01 DA014486NIDA NIH HHS R01 DA026430NIH HHS P51 OD010425NINDS NIH HHS R21 NS098777
6 · The paper itself

Abstract

The broad-based legalization of cannabis use has created a strong need to understand its impact on human health and behavior. The risks that may be associated with cannabis use, particularly for sensitive subgroups such as pregnant women, are difficult to define because of a paucity of dose-response data and the recent increase in cannabis potency. Although there is a large body of evidence detailing the mode of action of Δ

Indexed as

AnimalsBrainCognitionDronabinolFemaleHumansMarijuana UseModels, NeurologicalPregnancyPrenatal Exposure Delayed EffectsDronabinolCannabisChild developmentExposurePharmacokineticsPregnancy

Identifiers

PMID28847562
PMCPMC6211194

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.