ArticleUltrasound in medicine & biology2017
Combining Subharmonic and Ultraharmonic Modes for Intravascular Ultrasound Imaging: A Preliminary Evaluation.
Article in Ultrasound in medicine & biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Chirp-Coded Subharmonic Imaging With Volterra Filtering: Histotripsy Bubble Cloud Assessment In Vitro and Ex Vivo.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025Article
- Contrast-Enhanced Imaging of Histotripsy Bubble Clouds Using Chirp-Coded Excitation and Volterra Filtering.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023Article
- 3D Harmonic and Subharmonic Imaging for Characterizing Breast Lesions: A Multi-Center Clinical Trial.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2022Article
- On vasa vasorum: A history of advances in understanding the vessels of vessels.Science advances · 2022Review
- Histotripsy Bubble Cloud Contrast With Chirp-Coded Excitation in Preclinical Models.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022Article
- Estimating the mechanical energy of histotripsy bubble clouds with high frame rate imaging.Physics in medicine and biology · 2021Article
- High contrast power Doppler imaging in side-viewing intravascular ultrasound imaging via angular compounding.Ultrasonics · 2020Article
- Validation of Ultrasound Super-Resolution Imaging of Vasa Vasorum in Rabbit Atherosclerotic Plaques.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Contrast-enhanced intra-vascular ultrasound (CE-IVUS) imaging could provide clinicians a valuable tool to assess cardiovascular risk and guide the choice of therapeutic strategies. In this technical note, we evaluated the feasibility of combining subharmonic and ultraharmonic imaging to improve the performance of CE-IVUS. Vessel phantoms perfused with phospholipid-shelled ultrasound contrast agents were visualized using subharmonic, ultraharmonic and combined CE-IVUS modes with commercial peripheral and coronary imaging catheters. Flow channels as small as 0.8 mm and 0.5 mm were imaged at 12-MHz and 30-MHz transmit frequencies, respectively. Subharmonic and ultraharmonic imaging modes achieved a contrast-to-tissue ratio (CTR) up to 18.1 ± 1.8 dB and 19.6 ± 1.9 dB at 12-MHz, and 8.8 ± 1.8 and 12.5 ± 1.1 dB at 30-MHz transmit frequencies, respectively. Combining these modes improved the CTR to 32.5 ± 3.0 dB and 25.0 ± 1.6 dB at 12-MHz and 30-MHz transmit frequencies. These results underscore the potential of combined-mode CE-IVUS imaging. Furthermore, the demonstration of this approach with commercial catheters may serve as a first step toward the clinical translation of CE-IVUS.
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