ArticleThe Journal of organic chemistry2017
Cyclic Hexapeptide Dimers, Antatollamides A and B, from the Ascidian Didemnum molle. A Tryptophan-Derived Auxiliary for l- and d-Amino Acid Assignments.
Article in The Journal of organic chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Total Synthesis of Marine Natural Product Sunshinamide via Macrolactonization.Archiv der Pharmazie · 2026Article
- Structure and Synthesis of Amatyemides A and B, Cyclic Octadepsipeptides from South African Stromatolites.Journal of natural products · 2025Article
- Synthesis and Performance of l-Tryptophanamide and (The Journal of organic chemistry · 2025Article
- A Family of Nonribosomal Peptides Modulate Collective Behavior in Pseudovibrio Bacteria Isolated from Marine Sponges*.Angewandte Chemie (International ed. in English) · 2021Article
- Metabolomics Reveals Minor Tambjamines in a Marine Invertebrate Food Chain.Journal of natural products · 2021Article
- Secondary Metabolites of the GenusMarine drugs · 2020Review
- Genomics-driven discovery of a biosynthetic gene cluster required for the synthesis of BII-Rafflesfungin from the fungus Phoma sp. F3723.BMC genomics · 2019Article
- 6-Bromoindole Derivatives from the Icelandic Marine SpongeMarine drugs · 2018Article
- Ascidian Toxins with Potential for Drug Development.Marine drugs · 2018Review
- Marine Natural Peptides: Determination of Absolute Configuration Using Liquid Chromatography Methods and Evaluation of Bioactivities.Molecules (Basel, Switzerland) · 2018Review
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Authors and funding
2 authors.
Funding
Abstract
Two dimerized cyclic hexapeptides, antatollamides A (1) and B (2), were isolated from the colonial ascidian Didemnum molle collected in Pohnpei. The amino acid compositions and sequences were determined by interpretation of MS and 1D and 2D NMR data. Raney Ni reduction of antatollamide A cleaved the dimer to the corresponding monomeric cyclic hexapeptide with replacement of Cys by Ala. The amino acid configuration of 1 was established, after total hydrolysis, by derivatization with a new chiral reagent, (5-fluoro-2,4-dinitrophenyl)-N
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