Evidence map›Paper›PMID 28846480›Full record

ArticleHuman vaccines & immunotherapeutics2017

Influenza vaccine effectiveness against medically attended influenza illness in Beijing, China, 2014/15 season.

Chunna Ma, Yang Pan, Li Zhang, Yi Zhang, Shuangsheng Wu, Ying Sun, Wei Duan, Man Zhang, Quanyi Wang, Peng Yang

Open access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Chunna Maa Beijing Center for Disease Prevention and Control , Beijing , China.
Yang Pana Beijing Center for Disease Prevention and Control , Beijing , China.
Li Zhanga Beijing Center for Disease Prevention and Control , Beijing , China.
Yi Zhanga Beijing Center for Disease Prevention and Control , Beijing , China.
Shuangsheng Wua Beijing Center for Disease Prevention and Control , Beijing , China.
Ying Suna Beijing Center for Disease Prevention and Control , Beijing , China.
Wei Duana Beijing Center for Disease Prevention and Control , Beijing , China.
Man Zhanga Beijing Center for Disease Prevention and Control , Beijing , China.
Quanyi Wanga Beijing Center for Disease Prevention and Control , Beijing , China.
Peng Yanga Beijing Center for Disease Prevention and Control , Beijing , China.
Beijing Center for Disease Prevention and Control · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza vaccination is the most effective way of preventing influenza infections but its coverage is extremely low in China. Poor influenza vaccine effectiveness (VE) was reported in the 2014/15 season in some Northern Hemisphere countries with a predominance of H3N2 viruses belonging to the 3C.2a clade. However, there is limited information regarding the preventive effect of influenza vaccination for the same season in China, in which H3N2 viruses belonging to the 3C.3a clade predominated. Through influenza virological surveillance in Beijing, China during the 2014/15 season, we estimated the influenza VE against medically attended influenza-like illness (ILI) associated with laboratory-confirmed influenza virus infection using a test-negative design, and the effect of prior vaccination on current vaccination was examined. In total, 9297 patients with ILI were enrolled in this study. Among them, 3434 (36.9%) tested positive for influenza viruses: 2167 (63.1%) for A(H3N2), 1261 (36.7%) for influenza B, and 3 (0.1%) for A(H1N1)pdm09. The adjusted VE was estimated as -25% (95% CI: -70%, 8%) against A(H3N2) and -8% (95% CI: -50%, 23%) against B, with an overall VE of -18% (95% CI: -49%, 6%). The overall VE estimate for patients who received 2014/15 vaccination only was -12% (-57%, 20%), while VE for patients who received both 2013/14 and 2014/15 vaccinations was -27% (-72%, 7%). There was no evidence that the influenza vaccine protected vaccinees against medically attended influenza in Beijing, China during the 2014/15 season.

Indexed as

Vaccination CoverageVaccine PotencyAdolescentAdultCase-Control StudiesChildChild, PreschoolChinaFemaleHumansInfantInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza B virusInfluenza, HumanInfluenza VaccinesInfluenza VaccinesChinainfluenzainfluenza-like illnesstest-negative designvaccine effectiveness

Identifiers

PMID28846480
PMCPMC5647950
OpenAlexW2750232984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.