Evidence map›Paper›PMID 28845922›Full record

ReviewAdvanced healthcare materials2018

Three-Dimensional Models of the Human Brain Development and Diseases.

Mehdi Jorfi, Carla D'Avanzo, Doo Yeon Kim, Daniel Irimia

Open access · greenAbstract readReview
In one paragraph

Review in Advanced healthcare materials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
9.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 101 citations in OpenAlex.

  1. Article
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  11. 3D human stem-cell-derived neuronal spheroids forCurrent research in toxicology · 2024
    Article
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  15. Advances in currentFrontiers in bioengineering and biotechnology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mehdi JorfiCenter for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, 02129, USA.ORCID 0000-0003-4724-6190
Carla D'AvanzoGenetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, 02129, USA.
Doo Yeon KimGenetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, 02129, USA.
Daniel IrimiaCenter for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, 02129, USA.
Harvard University · US

Funding

TRANSGENICS AND PRESENILIN FUNCTIONP01AG015379 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI TANZI, RUDOLPH EMILE · 1998 to 2023
$51.3M
Bio-MicroElectroMechanical Systems Resource CenterP41EB002503 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI TONER, MEHMET · 2004 to 2018
$17.4M
Interdepartmental Neuroscience CenterP30NS045776 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI BREAKEFIELD, XANDRA OWENS, TANNOUS, BAKHOS A · 2003 to 2018
$11.1M
Role of the g-secretase/PS1 complex in APP processingR01AG014713 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI KIM, DOO YEON · 1997 to 2018
$5.9M
A novel human 3D neural cell culture system for the characterization of AD genesRF1AG048080 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI KIM, DOO YEON, TANZI, RUDOLPH EMILE · 2014 to 2014
$2.1M
Transient Obstruction of Capillary Networks by Chromatin Yarns from Neutrophils in Older AdultsR21AG051082 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI IRIMIA, DANIEL · 2015 to 2016
$479k
NIA NIH HHS P01 AG015379NIA NIH HHS R01 AG014713NIA NIH HHS R21 AG051082NIA NIH HHS RF1 AG048080NIBIB NIH HHS P41 EB002503NINDS NIH HHS P30 NS045776
6 · The paper itself

Abstract

Deciphering the human brain pathophysiology remains one of the greatest challenges of the 21

Indexed as

Alzheimer DiseaseBiocompatible MaterialsBrainCell Culture TechniquesHumansMicrofluidicsOrganoidsBiocompatible Materials3D culturebiomaterialsdisease modelingmicrofluidicsorganoids

Identifiers

PMID28845922
PMCPMC5762251
OpenAlexW2746144520

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.