Evidence map›Paper›PMID 28845614›Full record

ArticleObesity (Silver Spring, Md.)2017

Early Pregnancy Weight Gain Exerts the Strongest Effect on Birth Weight, Posing a Critical Time to Prevent Childhood Obesity.

Nicholas T Broskey, Peng Wang, Nan Li, Junhong Leng, Weiqin Li, Leishen Wang, L Anne Gilmore, Gang Hu, Leanne M Redman

Open access · greenAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Influence of Appetite and Perceived Ability to Control Cravings on Excessive Gestational Weight Gain.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Nicholas T BroskeyPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Peng WangTianjin Women's and Children's Health Center, Tianjin, China.
Nan LiTianjin Women's and Children's Health Center, Tianjin, China.
Junhong LengTianjin Women's and Children's Health Center, Tianjin, China.
Weiqin LiTianjin Women's and Children's Health Center, Tianjin, China.
Leishen WangTianjin Women's and Children's Health Center, Tianjin, China.
L Anne GilmorePennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Gang HuPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Leanne M RedmanPennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Tianjin Children's Hospital · CNPennington Biomedical Research Center · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2005 to 2026
$26.5M
Expecting Success: Personalized management of body weight during pregnancyU01DK094418 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI REDMAN, LEANNE MAREE · 2011 to 2015
$2.8M
Methylomics of prenatal GDM: Natural history & lifestyle intervention in childrenR01DK100790 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BACCARELLI, ANDREA, HOU, LIFANG · 2014 to 2017
$2.6M
Determinants of gestational weight gain in obese pregnant womenR01DK099175 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI REDMAN, LEANNE MAREE · 2013 to 2015
$1.8M
NIDDK NIH HHS P30 DK072476NIDDK NIH HHS R01 DK099175NIDDK NIH HHS R01 DK100790NIDDK NIH HHS U01 DK094418NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

objectiveGestational weight gain (GWG) is associated with infant birth weight and childhood obesity; however, the patterns of GWG on infant birth weight are poorly understood.

methodsThis analysis in 16,218 mother-child dyads from Tianjin, China, determined the risk of infant size at birth according to GWG occurring throughout the first and second trimester (early GWG) or during the third trimester (late GWG), according to maternal prepregnancy BMI and the 2009 Institute of Medicine recommendations.

resultsExcessive GWG in early and late pregnancy had an increased risk for large-for-gestational-age (LGA) infants (odds ratio [OR]: 2.4; 95% confidence interval [CI]: 1.5-4.0, P < 0.001). Regardless of prepregnancy BMI, excessive GWG early in pregnancy (< 24 weeks) was associated with an increased risk of LGA infants (OR: 2.5; 95% CI: 2.1-3.1, P < 0.001), and inadequate early GWG was associated with a higher risk of small-for-gestational-age (SGA) infants (OR: 1.4; 95% CI: 1.2-1.7, P < 0.001).

conclusionsThe pattern of GWG early in pregnancy, regardless of GWG later in pregnancy, had the greatest impact on infant size at birth. Interventions initiated early in pregnancy may facilitate better adherence to the GWG guidelines and minimize the risk of LGA and SGA infants, a potential precursor for childhood obesity.

Indexed as

Body Mass IndexAdultBirth WeightFemaleHumansInfantInfant, NewbornObesityPediatric ObesityPregnancyPregnancy ComplicationsRisk FactorsWeight GainYoung Adult

Identifiers

PMID28845614
PMCPMC5604854
OpenAlexW2751132774

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.