Evidence map›Paper›PMID 28845445›Full record

ArticleProceedings. Data Compression Conference

An Evaluation Framework for Lossy Compression of Genome Sequencing Quality Values.

Claudio Alberti, Noah Daniels, Mikel Hernaez, Jan Voges, Rachel L Goldfeder, Ana A Hernandez-Lopez, Marco Mattavelli, Bonnie Berger

Open access · greenAbstract read
In one paragraph

Article in Proceedings. Data Compression Conference. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. MZPAQ: a FASTQ data compression tool.Source code for biology and medicine · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Claudio AlbertiÉcole Polytechnique Fédérale de Lausanne EPFL - SCI-STI-MM Lausanne, VD Switzerland.
Noah DanielsMassachusetts Institute of Technology CSAIL & Mathematics. Cambridge, MA.
Mikel HernaezStanford University Electrical Engineering.
Jan VogesInstitut fuer Informationsverarbeitung (TNT) Leibniz Universität Hannover, Germany.
Rachel L GoldfederStanford University Biomedical Informatics.
Ana A Hernandez-LopezÉcole Polytechnique Fédérale de Lausanne EPFL - SCI-STI-MM Lausanne, VD Switzerland.
Marco MattavelliÉcole Polytechnique Fédérale de Lausanne EPFL - SCI-STI-MM Lausanne, VD Switzerland.
Bonnie BergerMassachusetts Institute of Technology CSAIL & Mathematics. Cambridge, MA.
École Polytechnique Fédérale de Lausanne · CHMassachusetts Institute of Technology · USStanford University · USInstitut für Informationsverarbeitung · DE

Funding

POSTDOCTORAL TRAINING IN MEDICAL INFORMATION SCIENCEST15LM007033 · NLM · STANFORD UNIVERSITY · PI SYLVIA KATINA PLEVRITIS · 1985 to 2026
$25.5M
Compressive genomics for large omics data sets: Algorithms applications & toolsR01GM108348 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BERGER, BONNIE · 2013 to 2019
$2.1M
Genomic Compression: From Information Theory to Parallel AlgorithmsU01CA198943 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI MILENKOVIC, OLGICA, WEISSMAN, TSACHY · 2015 to 2017
$1.4M
NCI NIH HHS U01 CA198943NIGMS NIH HHS R01 GM108348NLM NIH HHS T15 LM007033
6 · The paper itself

Abstract

This paper provides the specification and an initial validation of an evaluation framework for the comparison of lossy compressors of genome sequencing quality values. The goal is to define reference data, test sets, tools and metrics that shall be used to evaluate the impact of lossy compression of quality values on human genome variant calling. The functionality of the framework is validated referring to two state-of-the-art genomic compressors. This work has been spurred by the current activity within the ISO/IEC SC29/WG11 technical committee (a.k.a. MPEG), which is investigating the possibility of starting a standardization activity for genomic information representation.

Identifiers

PMID28845445
PMCPMC5568552
OpenAlexW2562306914

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.