Evidence map›Paper›PMID 28845428›Full record

ArticleERJ open research2017

Variations in the prevalence of childhood asthma and wheeze in MeDALL cohorts in Europe.

Eleonora P Uphoff, Philippa K Bird, Joseph Maria Antó, Mikel Basterrechea, Andrea von Berg, Anna Bergström, Jean Bousquet, Leda Chatzi, Maria Pia Fantini, Amparo Ferrero and 17 more

Abstract read
In one paragraph

Article in ERJ open research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Maternal prenatal psychological distress associates with offspring early-life wheezing - FinnBrain Birth Cohort.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Asthma-Associated Long TSLP Inhibits the Production of IgA.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Eleonora P UphoffBradford Institute for Health Research, Bradford, UK.
Philippa K BirdBradford Institute for Health Research, Bradford, UK.
Joseph Maria AntóInsituto de Salud Global Barcelona, Barcelona, Spain.
Mikel BasterrecheaCIBER Epidemiología y Salud Pública, Madrid, Spain.
Andrea von BergDept of Pediatrics, Marien Hospital Wesel, Wesel, Germany.
Anna BergströmInstitute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.
Jean BousquetCentre Hôpital Universitaire de Montpellier, Montpellier, France.
Leda ChatziDept of Social Medicine, University of Crete, Heraklion, Greece.
Maria Pia FantiniDipartimento di Scienze Biomediche e Neuromotorie, Universita degli Studi di Bologna, Bologna, Italy.
Amparo FerreroCIBER Epidemiología y Salud Pública, Madrid, Spain.
Ulrike GehringInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.
Davide GoriDipartimento di Scienze Biomediche e Neuromotorie, Universita degli Studi di Bologna, Bologna, Italy.
Joachim HeinrichInstitute of Epidemiology, Helmholtz Zentrum München, Munich, Germany.
Thomas KeilSocial Medicine, Epidemiology and Health Economics, Charité Medical University, Berlin, Germany.
Inger KullInstitute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.
Susanne LauPediatric Pneumology and Immunology, Charité Medical University, Berlin, Germany.
Dieter MaierBiomax Informatics AG, Planegg, Germany.
Isabelle MomasUniversité Paris Descartes, Paris, France.
Silvia NarduzziDipartimento di Epidemiologia del SSR del Lazio, Rome, Italy.
Daniela PortaDipartimento di Epidemiologia del SSR del Lazio, Rome, Italy.
Fanny RanciereUniversité Paris Descartes, Paris, France.
Theano RoumeliotakiDept of Social Medicine, University of Crete, Heraklion, Greece.
Tamara SchikowskiLeibniz-Institut für umweltmedizinische Forschung, Heinrich Heine Universitat, Düsseldorf, Germany.
Henriette A SmitJulius Center for Health Sciences and Primary Care, Public Health, Health Technology Assessment, Medical Humanities, University Medical Center Utrecht, Utrecht, The Netherlands.
Marie StandlInstitute of Epidemiology, Helmholtz Zentrum München, Munich, Germany.
Jordi SunyerInsituto de Salud Global Barcelona, Barcelona, Spain.
John WrightBradford Institute for Health Research, Bradford, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While there is evidence for variations in prevalence rates of childhood wheeze and asthma between countries, longitudinal, individual-level data are needed to understand these differences. The aim of this study was to examine variations in prevalence rates of childhood asthma, wheeze and wheeze with asthma in Europe. We analysed datasets from 10 MeDALL (Mechanisms of the Development of ALLergy) cohorts in eight countries, representing 26 663 children, to calculate prevalence rates of wheeze and asthma by child age and wheeze with asthma at age 4 years. Harmonised variables included outcomes parent-reported wheeze and parent-reported doctor-diagnosed asthma, and covariates maternal education, parental smoking, pets, parental asthma, doctor-diagnosed allergic rhinitis, doctor-diagnosed eczema and wheeze severity. At age 4 years, asthma prevalence varied from 1.72% in Germany to 13.48% in England and the prevalence of wheeze varied from 9.82% in Greece to 55.37% in Spain. Adjusted estimates of the proportion of 4-year-old children with wheeze diagnosed with asthma remained highest in England (38.14%, 95% CI 31.38-44.90%) and lowest in Spain (15.94%, 95% CI 6.16-25.71%). The large differences in prevalence rates of asthma, wheeze and wheeze with asthma at age 4 years between European cohorts may indicate that childhood asthma is more readily diagnosed in some countries while going unrecognised elsewhere.

Identifiers

PMID28845428
PMCPMC5566268

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.