Evidence map›Paper›PMID 28845319›Full record

ArticleCase reports in transplantation2017

Diagnostic Lessons from a Complex Case of Postintestinal Transplantation Enteropathy.

Cian Wade, Philip Allan, Elena Collantes, Srikanth R Reddy, Peter J Friend, Georgios Vrakas

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in transplantation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Cian WadeUniversity of Oxford Medical Sciences Division, Medical Sciences Office, JR Hospital, Headley Way, Oxford OX3 9DU, UK.ORCID 0000-0003-0949-0360
Philip AllanOxford University Hospitals NHS Foundation Trust, Oxford Transplant Centre, Churchill Hospital, Old Road, Oxford OX3 9DU, UK.
Elena CollantesDepartment of Cellular Pathology, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK.
Srikanth R ReddyOxford University Hospitals NHS Foundation Trust, Oxford Transplant Centre, Churchill Hospital, Old Road, Oxford OX3 9DU, UK.
Peter J FriendOxford University Hospitals NHS Foundation Trust, Oxford Transplant Centre, Churchill Hospital, Old Road, Oxford OX3 9DU, UK.
Georgios VrakasOxford University Hospitals NHS Foundation Trust, Oxford Transplant Centre, Churchill Hospital, Old Road, Oxford OX3 9DU, UK.
Churchill Hospital · GBJohn Radcliffe Hospital · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in the field of intestinal transplantation have been mitigated by the incidence of allograft rejection. In such events, early identification and appropriate timing of antirejection therapy are crucial in retaining graft function. We present the case of a patient who suffered severe postintestinal transplantation allograft enteropathy, primarily characterized by extensive mucosal ulcerations, and was refractory to all conventional therapy. This progressed as chronic rejection; however crucially this was not definitively diagnosed until allograft function had irreversibly diminished. We argue that the difficulties encountered in this case can be attributed to the inability of our current array of investigative studies and diagnostic guidelines to provide adequate clinical guidance. This case illustrates the importance of developing reliable and specific markers for guiding the diagnosis of rejection and the use of antirejection therapeutics in this rapidly evolving field of transplant surgery.

Identifiers

PMID28845319
PMCPMC5563400
OpenAlexW2744106390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.