ArticleCurrent biology : CB2017
Direct Electrical Stimulation in the Human Brain Disrupts Melody Processing.
Article in Current biology : CB, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- The feasibility and added value of mapping music during awake craniotomy: A systematic review.The European journal of neuroscience · 2022Pooled it
- Causal parametric language mapping with electrical stimulation during awake neurosurgery.Science advances · 2026Article
- Music and Affective Prosody after Surgical Removal of the Right Arcuate Fasciculus: A Case Study.Annals of the New York Academy of Sciences · 2025Article
- Causal Lesion Evidence for Two Motor Speech Coordination Networks in the Brain.bioRxiv : the preprint server for biology · 2025Article
- Article
- Intraoperative cortical localization of music and language reveals signatures of structural complexity in posterior temporal cortex.iScience · 2023Article
- Awake Craniotomy and Intraoperative Musical Performance for Brain Tumor Surgery: Case Report and Literature Review.Brain tumor research and treatment · 2023Article
- Brain Plasticity Reflects Specialized Cognitive Development Induced by Musical Training.Cerebral cortex communications · 2021Article
- Article
- A common neural signature of brain injury in concussion and subconcussion.Science advances · 2019Article
- Domain-Specific Diaschisis: Lesions to Parietal Action Areas Modulate Neural Responses to Tools in the Ventral Stream.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Task- and domain-specific modulation of functional connectivity in the ventral and dorsal object-processing pathways.Brain structure & function · 2018Article
- Predictive regulation and human design.eLife · 2018Article
- Reverse Engineering Tone-Deafness: Disrupting Pitch-Matching by Creating Temporary Dysfunctions in the Auditory-Motor Network.Frontiers in human neuroscience · 2018Article
- Direct electrical stimulation of the left frontal aslant tract disrupts sentence planning without affecting articulation.Cognitive neuropsychologyArticle
Corrections and comments
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Authors and funding
18 authors at 2 institutions in 1 country.
Funding
Abstract
Prior research using functional magnetic resonance imaging (fMRI) [1-4] and behavioral studies of patients with acquired or congenital amusia [5-8] suggest that the right posterior superior temporal gyrus (STG) in the human brain is specialized for aspects of music processing (for review, see [9-12]). Intracranial electrical brain stimulation in awake neurosurgery patients is a powerful means to determine the computations supported by specific brain regions and networks [13-21] because it provides reversible causal evidence with high spatial resolution (for review, see [22, 23]). Prior intracranial stimulation or cortical cooling studies have investigated musical abilities related to reading music scores [13, 14] and singing familiar songs [24, 25]. However, individuals with amusia (congenitally, or from a brain injury) have difficulty humming melodies but can be spared for singing familiar songs with familiar lyrics [26]. Here we report a detailed study of a musician with a low-grade tumor in the right temporal lobe. Functional MRI was used pre-operatively to localize music processing to the right STG, and the patient subsequently underwent awake intraoperative mapping using direct electrical stimulation during a melody repetition task. Stimulation of the right STG induced "music arrest" and errors in pitch but did not affect language processing. These findings provide causal evidence for the functional segregation of music and language processing in the human brain and confirm a specific role of the right STG in melody processing. VIDEO ABSTRACT.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.