SynthesisCurrent pain and headache reports2017
Alcohol Use as a Comorbidity and Precipitant of Primary Headache: Review and Meta-analysis.
Synthesis in Current pain and headache reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Association between wine consumption and migraine: a systematic review and meta-analysis of cross-sectional.Alcohol and alcoholism (Oxford, Oxfordshire) · 2025Pooled it
- A Global Perspective on Migraine Attack Triggers: Understanding Differences Across Lifestyles, Religions, and Regions.Current pain and headache reports · 2026Review
- Association Between the Frailty Index and Self-Reported Headache in Middle-Aged and Older Chinese Adults: An Analysis of the China Health and Retirement Longitudinal Study.Pain research & management · 2026Article
- Migraine and Alcohol-Is It Really That Harmful?Nutrients · 2025Review
- Headache disorders: a persistent public health challenge for the under 50s.Frontiers in neurology · 2024Article
- Inhibition of ALDH2 by quercetin glucuronide suggests a new hypothesis to explain red wine headaches.Scientific reports · 2023Article
- Acetaldehyde via CGRP receptor and TRPA1 in Schwann cells mediates ethanol-evoked periorbital mechanical allodynia in mice: relevance for migraine.Journal of biomedical science · 2023Article
- Explaining Disparities in Severe Headache and Migraine Among Sexual Minority Adults in the United States, 2013-2018.The Journal of nervous and mental disease · 2020Article
- Prospective cohort study of daily alcoholic beverage intake as a potential trigger of headaches among adults with episodic migraine.Annals of medicine · 2020Article
- Cohort profile: COpenhagen ROsacea COhort (COROCO) and COpenhagen MIgraine COhort (COMICO).BMJ open · 2020Article
- Sulfite concentration and the occurrence of headache in young adults: a prospective study.European journal of clinical nutrition · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewIn contrast to well-established relationships between headache and affective disorders, the role of alcohol use in primary headache disorders is less clear. This paper provides a narrative overview of research on alcohol use disorders (AUDs) in primary headache and presents a meta-analysis of the role of alcohol as a trigger (precipitant) of headache. RECENT
findingsThe majority of studies on AUDs in headache have failed to find evidence that migraine or tension-type headache (TTH) is associated with increased risk for AUDs or problematic alcohol use. The meta-analysis indicated that 22% (95% CI: 17-29%) of individuals with primary headache endorsed alcohol as a trigger. No differences were found between individuals with migraine (with or without aura) or TTH. Odds of endorsing red wine as a trigger were over 3 times greater than odds of endorsing beer. An absence of increased risk for AUDs among those with primary headache may be attributable to alcohol's role in precipitating headache attacks for some susceptible individuals. Roughly one fifth of headache sufferers believe alcohol precipitates at least some of their attacks. Considerable study heterogeneity limits fine-grained comparisons across studies and suggests needs for more standardized methods for studying alcohol-headache relationships and rigorous experimental designs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.