ReviewThe journal of allergy and clinical immunology. In practice
The 3 Cs of Antibiotic Allergy-Classification, Cross-Reactivity, and Collaboration.
Review in The journal of allergy and clinical immunology. In practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Assessment of the Frequency of Dual Allergy to Penicillins and Cefazolin: A Systematic Review and Meta-analysis.JAMA surgery · 2021Pooled it
- Delabeling penicillin allergies in plastic and reconstructive surgery: Cefazolin as the cornerstone for antibiotic prophylaxis.JPRAS open · 2026Review
- Drug-induced anaphylaxis: Molecular pathophysiology, diagnosis, and management.Asia Pacific allergy · 2026Article
- Nationwide survey on penicillin allergy delabeling among German healthcare professionals: knowledge, attitudes and perceived barriers.Infection · 2026Article
- Current status and challenges in the assessment of antibiotic allergy information in electronic health records: a retrospective observational study of perioperative patients.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Discrepancies in Beta-Lactam Antibiotics Cross-Reactivity: Implications for Clinical Practice.Allergy · 2025Article
- Single-Shot Perioperative Antibiotic Prophylaxis in Patients With a History of Penicillin Allergy: An Algorithm for the Safe Administration of Cefuroxime.Deutsches Arzteblatt international · 2025Observational
- National expert consensus on the management of antibiotic prophylaxis in surgical patients with a penicillin allergy label based on the Delphi method.JAC-antimicrobial resistance · 2025Article
- Evaluation of cephalosporin allergy: Survey of drug allergy experts.The journal of allergy and clinical immunology. Global · 2025Article
- Safety of Cefazolin in Pregnant Patients with Documented Penicillin Allergy: A Retrospective Cohort Study.The Canadian journal of hospital pharmacy · 2025Article
- Implementation and outcomes of beta-lactam allergy management protocol at a comprehensive cancer center.Infection · 2024Article
- Is the Anamnesis Enough to De-Label Patients with Reported Beta-Lactam Allergy?Journal of clinical medicine · 2024Article
- "What if the patient has a severe reaction, and it is my fault?" A qualitative study exploring factors for sustainable implementation of penicillin allergy delabelling.Antimicrobial resistance and infection control · 2024Article
- Leveraging implementation science theories to develop and expand the use of a penicillin allergy de-labeling intervention.BMC health services research · 2024Article
- Review
- Antibiotic-induced severe cutaneous adverse reactions: a single-center retrospective study over ten years.Frontiers in immunology · 2024Article
- Patient Adherence to Written Instructions following Complete Allergological Evaluation for Suspected Beta-Lactam Allergy: A Tertiary Hospital Study in Greece.Journal of personalized medicine · 2023Article
- Antibiotics-Related Adverse Drug Reaction in a Tertiary Hospital in Saudi Arabia: A Cohort, Retrospective Study.Cureus · 2023Article
- Development and implementation of "handshake rounds": An antibiotic stewardship intervention for hospitalized adult patients with hematologic malignancies.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Beta-lactam allergies, surgical site infections, and prophylaxis in solid organ transplant recipients at a single center: A retrospective cohort study.Transplant infectious disease : an official journal of the Transplantation Society · 2022Review
Corrections and comments
- Erratum issuedCorrigendum.2022
- Erratum issued
Authors and funding
7 authors.
Funding
Abstract
Antibiotic allergy labeling is highly prevalent and negatively impacts patient outcomes and antibiotic appropriateness. Reducing the prevalence and burden of antibiotic allergies requires the engagement of key stakeholders such as allergists, immunologists, pharmacists, and infectious diseases physicians. To help address this burden of antibiotic allergy overlabeling, we review 3 key antibiotic allergy domains: (1) antibiotic allergy classification, (2) antibiotic cross-reactivity, and (3) multidisciplinary collaboration. We review the available evidence and research gaps of currently used adverse drug reaction classification systems, antibiotic allergy cross-reactivity, and current and future models of antibiotic allergy care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.