ArticleJournal of biomedical materials research. Part B, Applied biomaterials2018
Zeolite-loaded alginate-chitosan hydrogel beads as a topical hemostat.
Article in Journal of biomedical materials research. Part B, Applied biomaterials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 71 citations in OpenAlex.
- Natural Clinoptilolite as a Functional Mineral Component in Alginate Hybrid Microcapsules for Controlled Amoxicillin Release.Pharmaceutics · 2026Article
- Preparation and Activity of Hemostatic and Antibacterial Dressings with Greige Cotton/Zeolite Formularies Having Silver and Ascorbic Acid Finishes.International journal of molecular sciences · 2023Article
- Multifunctional Sodium Hyaluronate/Chitosan Foam Used as an Absorbable Hemostatic Material.Bioengineering (Basel, Switzerland) · 2023Article
- A Comparison of Hemostatic Activities of Zeolite-Based Formulary Finishes on Cotton Dressings.Journal of functional biomaterials · 2023Article
- Recent advances in the medical applications of hemostatic materials.Theranostics · 2023Review
- Inorganic-based biomaterials for rapid hemostasis and wound healing.Chemical science · 2022Review
- Application of Alginate-Based Hydrogels in Hemostasis.Gels (Basel, Switzerland) · 2022Review
- Recent advances on polymeric hydrogels as wound dressings.APL bioengineering · 2021Review
- Development of a Nonwoven Hemostatic Dressing Based on Unbleached Cotton: A De Novo Design Approach.Pharmaceutics · 2020Article
- Biodegradable shape memory polymer foams with appropriate thermal properties for hemostatic applications.Journal of biomedical materials research. Part A · 2020Article
- Composite Hemostatic Nonwoven Textiles Based on Hyaluronic Acid, Cellulose, and Etamsylate.Materials (Basel, Switzerland) · 2020Article
- Computed tomography-guided additive manufacturing of Personalized Absorbable Gastrointestinal Stents for intestinal fistulae and perforations.Biomaterials · 2020Article
- Polymer nanomaterials for use as adjuvant surgical tools.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
Abstract
Hemorrhage is the leading cause of preventable death after a traumatic injury, and the largest contributor to loss of productive years of life. Hemostatic agents accelerate hemostasis and help control hemorrhage by concentrating coagulation factors, acting as procoagulants and/or interacting with erythrocytes and platelets. Hydrogel composites offer a platform for targeting both mechanical and biological hemostatic mechanisms. The goal of this work was to develop hydrogel particles composed of chitosan, alginate, and zeolite, and to assess their potential to promote blood coagulation via multiple mechanisms: erythrocyte adhesion, factor concentration, and the ability to serve as a mechanical barrier to blood loss. Several particle compositions were synthesized and characterized. Hydrogel bead composition was optimized to achieve the highest swelling capacity, greatest erythrocyte adhesion, and minimal in vitro cytotoxicity. These results suggest a polymer hydrogel-aluminosilicate composite material may serve as a platform for an effective hemostatic agent that incorporates multiple mechanisms of action. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1662-1671, 2018.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.