Evidence map›Paper›PMID 28842742›Full record

ArticleNeuroradiology2017

In vitro, contrast agent-based evaluation of the influence of flow diverter size and position on intra-aneurysmal flow dynamics using syngo iFlow.

Giorgio Franco Maria Cattaneo, Andreas Ding, Tobias Jost, Désirée Ley, Ruben Mühl-Bennighaus, Umut Yilmaz, Heiko Körner, Wolfgang Reith, Andreas Simgen

Abstract read
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In one paragraph

Article in Neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Experimental study using phantom models of cerebral aneurysms and 4D-DSA to measure blood flow on 3D-color-coded images.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Article
  3. Article
  4. Retrospective analysis of intracranial aneurysms after flow diverter treatment including color-coded imaging (syngo iFlow) as a predictor of aneurysm occlusion.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. 2D parametric contrast time-density analysis for the prediction of complete aneurysm occlusion at six months' post-flow diversion stent.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2020
    Article
  9. Article
  10. Quantitative color-coded digital subtraction neuroangiography for pediatric arteriovenous shunting lesions.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giorgio Franco Maria CattaneoAcandis GmbH, Theodor-Fahrner-Str. 6, 75177, Pforzheim, Germany. gcattaneo@acandis.com.
Andreas DingAcandis GmbH, Theodor-Fahrner-Str. 6, 75177, Pforzheim, Germany.
Tobias JostAcandis GmbH, Theodor-Fahrner-Str. 6, 75177, Pforzheim, Germany.
Désirée LeyDepartments of Neuroradiology, Saarland University Hospital, Homburg, Saar, Germany.
Ruben Mühl-BennighausDepartments of Neuroradiology, Saarland University Hospital, Homburg, Saar, Germany.
Umut YilmazDepartments of Neuroradiology, Saarland University Hospital, Homburg, Saar, Germany.
Heiko KörnerDepartments of Neuroradiology, Saarland University Hospital, Homburg, Saar, Germany.
Wolfgang ReithDepartments of Neuroradiology, Saarland University Hospital, Homburg, Saar, Germany.
Andreas SimgenDepartments of Neuroradiology, Saarland University Hospital, Homburg, Saar, Germany.

Funding

German Ministry of Economic Affairs and Energy KF2335801WL9
6 · The paper itself

Abstract

purposeTreatment of intracranial aneurysm with flow-diverting devices has become widespread in recent years. Despite that, intra-aneurysmal flow changes are yet not fully understood and can lead to different complications. Our aim was an in vitro contrast-based evaluation of the influence of flow diverter size and position on intra-aneurysmal flow dynamics.

methodsFlow-diverting devices with different sizes (diameters 4.0, 4.5, and 6.0 mm) were deployed in seven silicone aneurysm models at different positions relative to the aneurysm neck (proximal, central, distal). Using syngo iFlow, we defined quantitative evaluation criteria based on contrast medium intensity and performed a flow evaluation.

resultsIntra-aneurysmal flows were heavily dependent on both size and position of flow-diverting devices at the aneurysm neck. We observed a higher peak intensity delay and intra-aneurysmal washout delay with the centrally placed 4.0- and 4.5-mm device, respectively, compared to the proximal and distal positions. Especially distally placed 4.0-mm devices led to an earlier filling of the aneurysm and increased intra-aneurysmal contrast agent intensity compared to the parent vessel, due to a potential endoleak.

conclusionsNot only size but also position of flow-diverting devices have a considerable impact on the intra-aneurysmal flow dynamics. The suggested evaluation criteria allowed a quantitative comparison of flow-diverting effect using syngo iFlow and could represent an efficient tool for predicting flow diversion pre-procedurally.

Indexed as

Blood Flow VelocityStentsAngiography, Digital SubtractionCerebrovascular CirculationContrast MediaEquipment DesignImage Processing, Computer-AssistedIntracranial AneurysmIn Vitro TechniquesModels, AnatomicModels, CardiovascularSoftwareContrast MediaFlow diverteriFlowIntracranial aneurysmsStenting

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.