Evidence map›Paper›PMID 28842709›Full record

ArticleScientific reports2017

The Parkinson's disease-associated GPR37 receptor interacts with striatal adenosine A

Xavier Morató, Rafael Luján, Marc López-Cano, Jorge Gandía, Igor Stagljar, Masahiko Watanabe, Rodrigo A Cunha, Víctor Fernández-Dueñas, Francisco Ciruela

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Adenosine ACurrent issues in molecular biology · 2023
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Mouse Mutants ofInternational journal of molecular sciences · 2022
    Review
  16. Review
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Xavier MoratóUnitat de Farmacologia, Departament Patologia i Terapéutica Experimental, Facultat de Medicina, IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.
Rafael LujánIDINE, Departamento de Ciencias Médicas, Facultad de Medicina, Universidad Castilla-La Mancha, Albacete, Spain.
Marc López-CanoUnitat de Farmacologia, Departament Patologia i Terapéutica Experimental, Facultat de Medicina, IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.
Jorge GandíaUnitat de Farmacologia, Departament Patologia i Terapéutica Experimental, Facultat de Medicina, IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.
Igor StagljarDonnelly Centre, Department of Molecular Genetics, Department of Biochemistry, University of Toronto, Toronto, M5S 3E1, Canada.
Masahiko WatanabeDepartment of Anatomy, Hokkaido University School of Medicine, Sapporo, 060-0818, Japan.
Rodrigo A CunhaCNC-Center for Neuroscience and Cell Biology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
Víctor Fernández-DueñasUnitat de Farmacologia, Departament Patologia i Terapéutica Experimental, Facultat de Medicina, IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain. vfernandez@ub.edu.
Francisco CiruelaUnitat de Farmacologia, Departament Patologia i Terapéutica Experimental, Facultat de Medicina, IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain. fciruela@ub.edu.
Universitat de Barcelona · ESHokkaido University · JPInstitut d'Investigació Biomédica de Bellvitge · ESUniversity of Castilla-La Mancha · ESUniversity of Coimbra · PTUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

G protein-coupled receptor 37 (GPR37) is an orphan receptor associated to Parkinson's disease (PD) neuropathology. Here, we identified GPR37 as an inhibitor of adenosine A

Indexed as

AnimalsCatalepsyCyclic AMPDisease Models, AnimalGene Expression RegulationHumansLocomotionMaleMiceMice, Inbred C57BLMice, KnockoutParkinson DiseaseProtein MultimerizationReceptor, Adenosine A2AReceptors, G-Protein-CoupledSynapsesCyclic AMPGPR37 receptor, humanReceptor, Adenosine A2AReceptors, G-Protein-Coupled

Identifiers

PMID28842709
PMCPMC5573386
OpenAlexW2748894775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.