Evidence map›Paper›PMID 28842691›Full record

ArticleScientific reports2017

Poly-Methyl Methacrylate/Polyvinyl Alcohol Copolymer Agents Applied on Diabetic Wound Dressing.

Hsiao-Ting Hsieh, Hung-Ming Chang, Wei-Jhih Lin, Yao-Tsung Hsu, Fu-Der Mai

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hsiao-Ting HsiehGraduate Institute of Medical Science, College of Medicine, Taipei Medical University, No. 250 Wuxing St., Taipei, 11031, Taiwan.
Hung-Ming ChangDepartment of Anatomy and Cell Biology, School of Medicine, Taipei Medical University, No. 250 Wuxing St., Taipei, 11031, Taiwan.
Wei-Jhih LinDepartment of Forensic Science, Central Police University, No.56, Shuren Rd., Guishan Dist., Taoyuan City, 33304, Taiwan.
Yao-Tsung HsuDepartment of Biochemistry and Molecular Cell Biology, School of Medicine, Taipei Medical University, No. 250 Wuxing St., Taipei, 11031, Taiwan.
Fu-Der MaiGraduate Institute of Medical Science, College of Medicine, Taipei Medical University, No. 250 Wuxing St., Taipei, 11031, Taiwan. fordmai@tmu.edu.tw.
Taipei Medical University · TWCentral Police University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the difficulty of healing chronic wound, in the process of changing dressing, secondary damage on the tissue caused by adhesion should be prevented. In this study, the new dressing of particle hydrogels synthesized with poly-methyl methacrylate and poly-vinyl alcohol precursors were proposed. In addition, cell safety tests, animal's allergic stimulation, and animal's wound healing experiments were conducted for particle hydrogels. On one hand, in L929 cell experiment, the results of particle hydrogels extract 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide tests and lactate dehydrogenase test trial show that there are no safety concerns over particle hydrogels. On the other hand, New Zealand white rabbits were chosen for skin sensitization tests in animal trials, which show the consistent results. At last, wound healing tests used diabetes induction with 10-week-old rats and three-month-old Landrace pigs, with the tissue histology. In short, through this experiment, it is found that in the early phase of the diabetic rats and pigs' wound healing, using particle hydrogels can enhance collagen formation, and achieve the goal of faster wound healing.

Indexed as

BandagesAnimalsCell LineCell SurvivalCollagenDiabetes Mellitus, ExperimentalHydrogelsMiceNanowiresPolymersPolymethyl MethacrylatePolyvinyl AlcoholRabbitsRatsSilverSkinCollagenHydrogelsPolymersPolymethyl MethacrylatePolyvinyl AlcoholSilver

Identifiers

PMID28842691
PMCPMC5572720
OpenAlexW2750147589

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.