Evidence map›Paper›PMID 28842684›Full record

ArticleScientific reports2017

Plasmodium falciparum GPCR-like receptor SR25 mediates extracellular K

Miriam S Moraes, Alexandre Budu, Maneesh K Singh, Lucas Borges-Pereira, Julio Levano-Garcia, Chiara Currà, Leonardo Picci, Tomasino Pace, Marta Ponzi, Tullio Pozzan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Changes in KInternational journal of molecular sciences · 2023
    Review
  4. Article
  5. Review
  6. TrkA serves as a virulence modulator inFrontiers in cellular and infection microbiology · 2022
    Article
  7. Evidence of G-Protein-Coupled Receptors (GPCR) in the Parasitic ProtozoaInternational journal of molecular sciences · 2021
    Review
  8. Review
  9. Review
  10. Intracellular CaInternational journal of molecular sciences · 2021
    Review
  11. Calcium in the Backstage of Malaria Parasite Biology.Frontiers in cellular and infection microbiology · 2021
    Review
  12. Article
  13. Article
  14. Review
  15. Biomolecules · 2020
    Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 4 countries.

Miriam S MoraesDepartamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, Sao Paulo, SP, 05508-090, Brazil.
Alexandre BuduDepartamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, Sao Paulo, SP, 05508-090, Brazil.
Maneesh K SinghDepartamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, Sao Paulo, SP, 05508-090, Brazil.
Lucas Borges-PereiraDepartamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, Sao Paulo, SP, 05508-090, Brazil.
Julio Levano-GarciaDepartamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, Sao Paulo, SP, 05508-090, Brazil.ORCID 0000-0001-8140-5568
Chiara CurràDepartamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, Sao Paulo, SP, 05508-090, Brazil.
Leonardo PicciIstituto Superiore di Sanita, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, 0161, Roma, Italy.
Tomasino PaceIstituto Superiore di Sanita, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, 0161, Roma, Italy.
Marta PonziIstituto Superiore di Sanita, Dipartimento di Malattie Infettive, Parassitarie ed Immunomediate, 0161, Roma, Italy.
Tullio PozzanDepartment of Biomedical Sciences, University of Padova, Institute of Neuroscience, Padova, Unit, National Research Council, Venetian Institute of Molecular Medicine, Padova, Italy.
Célia R S GarciaDepartamento de Fisiologia, Instituto de Biociências, Universidade de São Paulo, Sao Paulo, SP, 05508-090, Brazil. cgarcia@usp.br.
Universidade de São Paulo · BRIstituto Superiore di Sanità · ITVeneto Institute of Molecular Medicine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The malaria parasite Plasmodium falciparum is exposed, during its development, to major changes of ionic composition in its surrounding medium. We demonstrate that the P. falciparum serpentine-like receptor PfSR25 is a monovalent cation sensor capable of modulating Ca

Indexed as

Calcium SignalingStress, PhysiologicalErythrocytesGene Expression RegulationMalaria, FalciparumParasite LoadPlasmodium falciparumPotassiumProtozoan ProteinsReceptors, G-Protein-CoupledPotassiumProtozoan ProteinsReceptors, G-Protein-Coupled

Identifiers

PMID28842684
PMCPMC5573319
OpenAlexW2749891110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.