ArticleScientific reports2017
US-Guided Percutaneous Radiofrequency versus Microwave Ablation for Benign Thyroid Nodules: A Prospective Multicenter Study.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06426563 (Microwave Ablation Versus Radiofrequency Ablation for the Treatment of Moderate-sized Benign Thyroid Nodules, a Randomized Controlled Trial), which is not on this map. Cited by 49 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Microwave Ablation Versus Radiofrequency Ablation for the Treatment of Moderate-sized Benign Thyroid Nodules, a Randomized Controlled Trial
Who cites it
49 citing papers in PubMed, 5 syntheses or guidelines pooled it, 116 citations in OpenAlex.
- Complications of minimally invasive treatments of benign thyroid nodules: preventive andmanaging strategies: A systematic review.La Radiologia medica · 2026Pooled it
- The long-term effects of thermal ablation for benign thyroid nodules: a systematic review and meta-analysis.European radiology · 2025Pooled it
- Comparative efficacy and safety of radiofrequency ablation and microwave ablation in benign thyroid nodule treatment: a systematic review and meta-analysis.European radiology · 2025Pooled it
- Comparative Efficacy and Safety of Radiofrequency Ablation and Microwave Ablation in the Treatment of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis.Korean journal of radiology · 2024Pooled it
- Pooled it
- Radiofrequency versus microwave ablation for non-functioning benign thyroid nodules: a single-institution comparative cohort study.Endocrine · 2026Article
- The efficacy and safety of microwave ablation in benign large thyroid nodules (≥4 cm).European thyroid journal · 2026Article
- Microwave Ablation Versus Thyroid Lobectomy for Solitary cT1aN0M0 Papillary Thyroid Carcinoma: A Prospective Multicenter Cohort Study.Mayo Clinic proceedings. Innovations, quality & outcomes · 2026Article
- Single-session radiofrequency ablation versus microwave ablation of predominantly solid benign thyroid nodules-a comparison after propensity score matching for initial nodule volumes and diameters.European radiology · 2026Article
- Comparing the therapeutic efficacy of radiofrequency vs. Microwave ablation for non-functioning benign thyroid nodules.Journal of endocrinological investigation · 2026Article
- Thyroid function alterations after radiofrequency ablation in benign thyroid nodule management.Therapeutic advances in endocrinology and metabolism · 2026Article
- Comparison of two ablation methods in benign thyroid nodules: Radiofrequency ablation and non-cooled microwave ablation.Journal of clinical imaging science · 2026Article
- Efficacy, safety, and risk factors of thermal ablation for follicular thyroid neoplasms: a multicentric study.Endocrine · 2025Article
- Microwave ablation of thyroid nodules and metastatic thyroid cervical lymph nodes: the first case series from Ecuador.Journal of surgical case reports · 2025Article
- Microwave ablation: a technical and clinical comparison to other thermal ablation modalities to treat benign and malignant thyroid nodules.Gland surgery · 2024Review
- Protect the recurrent laryngeal nerves in US-guided microwave ablation of thyroid nodules at Zuckerkandl tubercle: a pilot study.BMC cancer · 2024Article
- Radiofrequency ablation of thyroid nodules: a clinical review of treatment complications.Gland surgery · 2024Review
- A prognostic model for thermal ablation of benign thyroid nodules based on interpretable machine learning.Frontiers in endocrinology · 2024Article
- Brazilian Consensus on the Application of Thermal Ablation for Treatment of Thyroid Nodules: A Task Force Statement by the Brazilian Society of Interventional Radiology and Endovascular Surgery (SOBRICE), Brazilian Society of Head and Neck Surgery (SBCCP), and Brazilian Society of Endocrinology and Metabolism (SBEM).Archives of endocrinology and metabolism · 2024Article
- General Principles for the Safe Performance, Training, and Adoption of Ablation Techniques for Benign Thyroid Nodules: An American Thyroid Association Statement.Thyroid : official journal of the American Thyroid Association · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Compared with microwave ablation (MWA), percutaneous radiofrequency ablation (RFA) and laser ablation (LA) have been recommended as minimally invasive treatments for patients with symptomatic benign thyroid nodules (BTNs) because of the large number of clinical applications. This prospective multicenter study sought to evaluate the clinical outcomes of RFA and MWA for BTNs. In eight participating institutions, the total number of 1252 patients treated by RFA and MWA were 649 ones with 687 BTNs and 603 ones with 664 BTNs, respectively. The clinical outcomes including the nodular maximal diameter reduction ratio (MDRR), the nodular volume reduction ratio (VRR), and the incidence of complications were compared to evaluate the efficacy and safety of the two techniques. The results for the nodular MDRR and VRR in the RFA group were significantly better than those in the MWA group at 6 months and later follow-up, and the major complication rates of 4.78% and 6.63% in RFA and MWA groups showed no statistically significant differences. In conclusion, both RFA and MWA are safe and effective techniques for selected patients with symptomatic BTNs. The achieved MDRR and VRR in the RFA group were greater than those in the MWA group at 6 months and later follow-up.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.