ArticleScientific reports2017
No evidence for manipulation of Anopheles gambiae, An. coluzzii and An. arabiensis host preference by Plasmodium falciparum.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- The brain of the female Anopheles gambiae mosquito at spatial and single-cell resolution.Nature communications · 2026Article
- À la carte: how mosquitoes choose their blood meals.Trends in parasitology · 2024Review
- Development of circulating isolates of Plasmodium falciparum is accelerated in Anopheles vectors with reduced reproductive output.PLoS neglected tropical diseases · 2024Article
- Manipulation by Plasmodium Parasites of Anopheles Mosquito Behavior and Human Odors.Acta parasitologica · 2022Review
- No evidence for long-range male sex pheromones in two malaria mosquitoes.Nature ecology & evolution · 2022Article
- Transcriptome profiles of Anopheles gambiae harboring natural low-level Plasmodium infection reveal adaptive advantages for the mosquito.Scientific reports · 2021Article
- Differential attraction in mosquito-human interactions and implications for disease control.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Olfaction in Anopheles mosquitoes.Chemical senses · 2021Review
- Non-immune Traits Triggered by Blood Intake Impact Vectorial Competence.Frontiers in physiology · 2021Review
- Effect of irradiation on the survival and susceptibility of female Anopheles arabiensis to natural isolates of Plasmodium falciparum.Parasites & vectors · 2020Article
- Avian malaria alters the dynamics of blood feeding in Culex pipiens mosquitoes.Malaria journal · 2019Article
- Species-specific alterations in Anopheles mosquito olfactory responses caused by Plasmodium infection.Scientific reports · 2019Article
- Transmission traits of malaria parasites within the mosquito: Genetic variation, phenotypic plasticity, and consequences for control.Evolutionary applications · 2018Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whether malaria parasites can manipulate mosquito host choice in ways that enhance parasite transmission toward suitable hosts and/or reduce mosquito attraction to unsuitable hosts (i.e. specific manipulation) is unknown. To address this question, we experimentally infected three species of mosquito vectors with wild isolates of the human malaria parasite Plasmodium falciparum, and examined the effects of immature and mature infections on mosquito behavioural responses to combinations of calf odour, human odour and outdoor air using a dual-port olfactometer. Regardless of parasite developmental stage and mosquito species, P. falciparum infection did not alter mosquito activation rate or their choice for human odours. The overall expression pattern of host choice of all three mosquito species was consistent with a high degree of anthropophily, with infected and uninfected individuals showing higher attraction toward human odour over calf odour, human odour over outdoor air, and outdoor air over calf odour. Our results suggest that, in this system, the parasite may not be able to manipulate the early long-range behavioural steps involved in the mosquito host-feeding process. Future studies are required to test whether malaria parasites can modify their mosquito host choice at a shorter range to enhance transmission.
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