Evidence map›Paper›PMID 28842604›Full record

ArticleScientific reports2017

Neuroprotective effect of kinin B1 receptor activation in acute cerebral ischemia in diabetic mice.

Dorinne Desposito, Georges Zadigue, Christopher Taveau, Clovis Adam, François Alhenc-Gelas, Nadine Bouby, Ronan Roussel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Mastoparan M extracted fromIranian journal of basic medical sciences · 2022
    Article
  4. Article
  5. Review
  6. Kinins and Kinin Receptors in Cardiovascular and Renal Diseases.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Dorinne DespositoINSERM U 1138, Cordeliers Research Center, Paris, France.
Georges ZadigueINSERM U 1138, Cordeliers Research Center, Paris, France.
Christopher TaveauINSERM U 1138, Cordeliers Research Center, Paris, France.
Clovis AdamAnatomopathology Department, Kremlin-Bicêtre Hospital, Paris, France.
François Alhenc-GelasINSERM U 1138, Cordeliers Research Center, Paris, France.
Nadine BoubyINSERM U 1138, Cordeliers Research Center, Paris, France. nadine.bouby@crc.jussieu.fr.
Ronan RousselINSERM U 1138, Cordeliers Research Center, Paris, France.
Centre de Recherche des Cordeliers · FRInserm · FRBicêtre Hospital · FRDélégation Paris 5 · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of the kallikrein-kinin system enhances cardiac and renal tolerance to ischemia. Here we investigated the effects of selective agonists of kinin B1 or B2 receptor (R) in brain ischemia-reperfusion in diabetic and non-diabetic mice. The role of endogenous kinins was assessed in tissue kallikrein deficient mice (TK

Indexed as

AnimalsBrain IschemiaDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 1HemodynamicsInfarction, Middle Cerebral ArteryMaleMice, Inbred C57BLNeuroprotective AgentsReceptor, Bradykinin B1Receptor, Bradykinin B2Renal InsufficiencyNeuroprotective AgentsReceptor, Bradykinin B1Receptor, Bradykinin B2

Identifiers

PMID28842604
PMCPMC5572700
OpenAlexW2745416706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.