Evidence map›Paper›PMID 28842603›Full record

ArticleScientific reports2017

Virtual histological assessment of the prenatal life history and age at death of the Upper Paleolithic fetus from Ostuni (Italy).

Alessia Nava, Alfredo Coppa, Donato Coppola, Lucia Mancini, Diego Dreossi, Franco Zanini, Federico Bernardini, Claudio Tuniz, Luca Bondioli

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
19.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Variation in Modern Human Deciduous Molar Enamel Formation Time.American journal of biological anthropology · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. The obstetrical dilemma hypothesis: there's life in the old dog yet.Biological reviews of the Cambridge Philosophical Society · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Alessia NavaDipartimento di Biologia Ambientale, Università di Roma "La Sapienza", Rome, Italy. alessia.nava@uniroma1.it.ORCID 0000-0002-6319-0425
Alfredo CoppaDipartimento di Biologia Ambientale, Università di Roma "La Sapienza", Rome, Italy.
Donato CoppolaUniversità degli Studi di Bari "Aldo Moro", Bari, Italy.
Lucia ManciniElettra - Sincrotrone Trieste S.C.p.A., Basovizza, Trieste, Italy.
Diego DreossiElettra - Sincrotrone Trieste S.C.p.A., Basovizza, Trieste, Italy.
Franco ZaniniElettra - Sincrotrone Trieste S.C.p.A., Basovizza, Trieste, Italy.
Federico BernardiniCentro Fermi, Museo Storico della Fisica e Centro di Studi e Ricerche "Enrico Fermi", Piazza del Viminale 1, 00184, Roma, Italy.
Claudio TunizCentro Fermi, Museo Storico della Fisica e Centro di Studi e Ricerche "Enrico Fermi", Piazza del Viminale 1, 00184, Roma, Italy.
Luca BondioliServizio di Bioarcheologia, Museo delle Civiltà, Rome, Italy.
Elettra-Sincrotrone Trieste S.C.p.A. · ITMuseo Galileo · ITThe Abdus Salam International Centre for Theoretical Physics (ICTP) · ITMuseo Egizio · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fetal remains from the Ostuni 1 burial (Italy, ca 27 ka) represent a unique opportunity to explore the prenatal biological parameters, and to reconstruct the possible patho-biography, of a fetus (and its mother) in an Upper Paleolithic context. Phase-contrast synchrotron X-ray microtomography imaging of two deciduous tooth crowns and microfocus CT measurements of the right hemimandible of the Ostuni 1b fetus were performed at the SYRMEP beamline and at the TomoLab station of the Elettra - Sincrotrone laboratory (Trieste, Italy) in order to refine age at death and to report the enamel developmental history and dental tissue volumes for this fetal individual. The virtual histology allowed to estimate the age at death of the fetus at 31-33 gestational weeks. Three severe physiological stress episodes were also identified in the prenatal enamel. These stress episodes occurred during the last two months and half of pregnancy and may relate to the death of both individuals. Compared with modern prenatal standards, Os1b's skeletal development was advanced. This cautions against the use of modern skeletal and dental references for archaeological finds and emphasizes the need for more studies on prenatal archaeological skeletal samples.

Indexed as

ArchaeologyAutopsyPrenatal DiagnosisBurialFemaleFetusHumansItalyPregnancyX-Ray Microtomography

Identifiers

PMID28842603
PMCPMC5572742
OpenAlexW2747995477

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.