Evidence map›Paper›PMID 28842497›Full record

ArticleThe Journal of biological chemistry2017

The binding of activated Gα

Punya Navaratnarajah, Anne Gershenson, Elliott M Ross

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. AInternational journal of molecular sciences · 2024
    Article
  4. DAPLE protein inhibits nucleotide exchange on GαThe Journal of biological chemistry · 2020
    Article
  5. Phospholipase C.Advances in experimental medicine and biology · 2020
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Punya NavaratnarajahFrom the Department of Pharmacology and Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9041 and.ORCID 0000-0001-8377-9985
Anne Gershensonthe Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts 01003-9292.ORCID 0000-0003-3124-9610
Elliott M RossFrom the Department of Pharmacology and Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9041 and Elliott.Ross@UTSouthwestern.edu.ORCID 0000-0002-0252-8197
Center for Systems Biology · USSouthwestern Medical Center · USUniversity of Massachusetts Amherst · US

Funding

G Protein-Coupled Receptors-Structure and RegulationR01GM030355 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI ROSS, ELLIOTT M · 1985 to 2015
$5.0M
ACTIVATION OF PI-SPECIFIC PHOSPHOLIPASE C ENZYMESR01GM060418 · NIGMS · BOSTON COLLEGE · PI ROBERTS, MARY FEDARKO · 2000 to 2013
$3.1M
Laser Scanning Confocal for UT Southwestern Live Cell Imaging FacilityS10OD021684 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI LUBY-PHELPS, KATHERINE J · 2016 to 2016
$455k
GTPase Activating Protein for Golf and Gs in Olfactory NeuronsR21DC015744 · NIDCD · UT SOUTHWESTERN MEDICAL CENTER · PI ROSS, ELLIOTT M · 2016 to 2017
$445k
NIDCD NIH HHS R21 DC015744NIGMS NIH HHS R01 GM030355NIGMS NIH HHS R01 GM060418NIH HHS S10 OD021684
6 · The paper itself

Abstract

Upon activation by the G

Indexed as

Models, ChemicalAllosteric RegulationCalciumEnzyme ActivationFluorescence Resonance Energy TransferGTP-Binding Protein alpha Subunits, Gq-G11HumansIsoenzymesKineticsPhospholipase C betaProtein BindingCalciumGNAQ protein, humanGTP-Binding Protein alpha Subunits, Gq-G11IsoenzymesPhospholipase C betaenzyme kineticsfluorescence correlation spectroscopy (FCS)fluorescence resonance energy transfer (FRET)heterotrimeric G proteinphosphatidylinositol signalingphospholipase C

Identifiers

PMID28842497
PMCPMC5633138
OpenAlexW2747885924

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.