Evidence map›Paper›PMID 28842483›Full record

ArticleThe Journal of biological chemistry2017

Cell-cell adhesion in metazoans relies on evolutionarily conserved features of the α-catenin·β-catenin-binding interface.

Xiangqiang Shao, Hyunook Kang, Timothy Loveless, Gyu Rie Lee, Chaok Seok, William I Weis, Hee-Jung Choi, Jeff Hardin

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Single-molecule force spectroscopy reveals intra- and intermolecular interactions ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
  5. Potential Therapeutic Applications of N-Cadherin Antagonists and Agonists.Frontiers in cell and developmental biology · 2022
    Review
  6. Review
  7. The adhesion modulation domain ofMolecular biology of the cell · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Xiangqiang ShaoFrom the Program in Genetics.
Hyunook Kangthe Departments of Biological Sciences and.
Timothy LovelessDepartment of Zoology, and.
Gyu Rie LeeChemistry, Seoul National University, Seoul 08826, South Korea, and.
Chaok SeokChemistry, Seoul National University, Seoul 08826, South Korea, and.ORCID 0000-0002-1419-9888
William I Weisthe Departments of Structural Biology and Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California 94305.ORCID 0000-0002-5583-6150
Hee-Jung Choithe Departments of Biological Sciences and.ORCID 0000-0002-1468-4074
Jeff HardinFrom the Program in Genetics, choihj@snu.ac.kr.ORCID 0000-0001-7399-6580
Seoul National University · KRUniversity of Wisconsin–Madison · USInstitut thématique Génétique, génomique et bioinformatique · FRStanford University · US

Funding

X-ray Absorption Spectroscopy (XAS) pp.711-759P41GM103393 · NIGMS · STANFORD UNIVERSITY · PI HODGSON, KEITH O · 2012 to 2019
$30.6M
Assemby , dynamics and evolution of cell-cell and cell-matrix adhesionsU01GM094663 · NIGMS · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI LIDDINGTON, ROBERT COLIN · 2010 to 2014
$6.4M
Tension-dependent regulation of alpha-catenin during morphogenesis in C. elegansR01GM058038 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HARDIN, JEFFREY D · 1998 to 2021
$6.2M
Understanding force-dependent binding of alpha-catenin to actinR01GM114462 · NIGMS · STANFORD UNIVERSITY · PI DUNN, ALEXANDER R, WEIS, WILLIAM I · 2015 to 2018
$1.2M
NIGMS NIH HHS P41 GM103393NIGMS NIH HHS R01 GM058038NIGMS NIH HHS R01 GM114462NIGMS NIH HHS U01 GM094663
6 · The paper itself

Abstract

Stable tissue integrity during embryonic development relies on the function of the cadherin·catenin complex (CCC). The

Indexed as

alpha CateninAmino Acid SubstitutionAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell AdhesionCell CommunicationCrystallography, X-RayCytoskeletal ProteinsMultiprotein ComplexesMutation, MissenseProtein Structure, Quaternaryalpha CateninCaenorhabditis elegans ProteinsCytoskeletal ProteinsHMP-1 protein, C elegansHMP-2 protein, C elegansMultiprotein Complexesadherens junctioncadherin-catenin complexcrystal structuremorphogenesisphosphoregulationα-cateninβ-catenin

Identifiers

PMID28842483
PMCPMC5633108
OpenAlexW2748034654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.