Evidence map›Paper›PMID 28842475›Full record

ArticleThe Journal of biological chemistry2017

Shining a light on GPCR complexes.

Carmen W Dessauer

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Carmen W DessauerFrom the Department of Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center, Houston, Texas 77030. Electronic address: carmen.w.dessauer@uth.tmc.edu.
The University of Texas Health Science Center at Houston · US

Funding

REGULATION OF ADENYLYL CYCLASE SIGNALING PATHWAYSR01GM060419 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI DESSAUER, CARMEN W. · 2000 to 2021
$6.9M
Mechanisms of cAMP signaling that drive spontaneous activity in nociceptorsR01NS091759 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Carmen W. Dessauer, EDGAR T. WALTERS · 2015 to 2026
$4.9M
NIGMS NIH HHS R01 GM060419NINDS NIH HHS R01 NS091759
6 · The paper itself

Abstract

The G protein-coupled receptor (GPCR) signaling pathways mediating information exchange across the cell membrane are central to a variety of biological processes and therapeutic strategies, but visualizing the molecular-level details of this exchange has been difficult for all but a few GPCR-G protein complexes. A study by Gao

Indexed as

Models, MolecularAnimalsEye ProteinsGTP-Binding Protein beta SubunitsGTP-Binding Protein gamma SubunitsHumansProtein Interaction Domains and MotifsProtein MultimerizationRhodopsinRod Cell Outer SegmentTransducinEye ProteinsGTP-Binding Protein beta SubunitsGTP-Binding Protein gamma SubunitsRhodopsinTransducin

Identifiers

PMID28842475
PMCPMC5572900
OpenAlexW2750353530

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.