Evidence map›Paper›PMID 28842363›Full record

ArticleBone2017

Associations between body mass index across adult life and hip shapes at age 60 to 64: Evidence from the 1946 British birth cohort.

Stella G Muthuri, Fiona R Saunders, Rebecca J Hardy, Anastasia V Pavlova, Kathryn R Martin, Jennifer S Gregory, Rebecca J Barr, Judith E Adams, Diana Kuh, Richard M Aspden and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Bone, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Age at Onset of Walking in Infancy Is Associated With Hip Shape in Early Old Age.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019
    Trial
  2. Article
  3. Article
  4. Article
  5. Motor development in infancy and spine shape in early old age: Findings from a British birth cohort study.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
    Article
  6. The importance of hip shape in predicting hip osteoarthritis.Current treatment options in rheumatology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Stella G MuthuriMRC Unit for Lifelong Health and Ageing at UCL, 33 Bedford Place, London WC1B 5JU, UK. Electronic address: s.muthuri@ucl.ac.uk.
Fiona R SaundersAberdeen Centre for Arthritis and Musculoskeletal Health, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Rebecca J HardyMRC Unit for Lifelong Health and Ageing at UCL, 33 Bedford Place, London WC1B 5JU, UK.
Anastasia V PavlovaAberdeen Centre for Arthritis and Musculoskeletal Health, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Kathryn R MartinAberdeen Centre for Arthritis and Musculoskeletal Health, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Jennifer S GregoryAberdeen Centre for Arthritis and Musculoskeletal Health, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Rebecca J BarrMedicines Monitoring Unit (MEMO), Division of Molecular & Clinical Medicine, School of Medicine, University of Dundee, Mailbox 2 Level 7, Ninewells Hospital & Medical School, Dundee DD1 9SY, UK.
Judith E AdamsManchester Academic Health Science Centre and Radiology, Central Manchester University Hospitals NHS Foundation Trust and University of Manchester, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.
Diana KuhMRC Unit for Lifelong Health and Ageing at UCL, 33 Bedford Place, London WC1B 5JU, UK.
Richard M AspdenAberdeen Centre for Arthritis and Musculoskeletal Health, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Rachel CooperMRC Unit for Lifelong Health and Ageing at UCL, 33 Bedford Place, London WC1B 5JU, UK.
University College London · GBMRC Unit for Lifelong Health and Ageing · GBNinewells Hospital · GBUniversity of Manchester · GB

Funding

Medical Research Council MC_UU_12019/2Medical Research Council MC_UU_12019/4Medical Research Council MR/L010399/1Wellcome Trust
6 · The paper itself

Abstract

objectiveTo examine the associations of body mass index (BMI) across adulthood with hip shapes at age 60-64years.

methodsUp to 1633 men and women from the MRC National Survey of Health and Development with repeat measures of BMI across adulthood and posterior-anterior dual-energy X-ray absorptiometry bone mineral density images of the proximal femur recorded at age 60-64 were included in analyses. Statistical shape modelling was applied to quantify independent variations in hip mode (HM), of which the first 6 were examined in relation to: i) BMI at each age of assessment; ii) BMI gain during different phases of adulthood; iii) age first overweight.

resultsHigher BMI at all ages (i.e. 15 to 60-64) and greater gains in BMI were associated with higher HM2 scores in both sexes (with positive HM2 values representing a shorter femoral neck and a wider and flatter femoral head). Similarly, younger age first overweight was associated with higher HM2 scores but only in men once current BMI was accounted for. In men, higher BMI at all ages was also associated with lower HM4 scores (with negative HM4 values representing a flatter femoral head, a wider neck and smaller neck shaft angle) but no associations with BMI gain or prolonged exposure to high BMI were found. Less consistent evidence of associations was found between BMI and the other four HMs.

conclusionThese results suggest that BMI across adulthood may be associated with specific variations in hip shapes in early old age.

Indexed as

Body Mass IndexParturitionAdultCohort StudiesFemaleHipHumansMaleMiddle AgedYoung AdultBody mass indexHip shapeLife course epidemiologyStatistical shape modelling

Identifiers

PMID28842363
PMCPMC5658512
OpenAlexW2606494363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.