Evidence map›Paper›PMID 28842222›Full record

ArticleExperimental gerontology2017

Physical performance and movement-evoked pain profiles in community-dwelling individuals at risk for knee osteoarthritis.

Yenisel Cruz-Almeida, Josue Cardoso, Joseph L Riley, Burel Goodin, Christopher D King, Megan Petrov, Emily J Bartley, Kimberly T Sibille, Toni L Glover, Matthew S Herbert and 6 more

Abstract readMulticenter Study
In one paragraph

Article in Experimental gerontology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 65 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Yenisel Cruz-AlmeidaPain Research & Intervention Center of Excellence, University of Florida, USA; Institute on Aging, University of Florida, USA; Cognitive Aging & Memory Clinical Translational Research Program, University of Florida, USA; Department of Aging & Geriatric Research, College of Medicine, University of Florida, USA; Department of Neuroscience, College of Medicine, University of Florida, USA; Department of Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, USA. Electronic address: cryeni@ufl.edu.
Josue CardosoPain Research & Intervention Center of Excellence, University of Florida, USA; Department of Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, USA.
Joseph L RileyPain Research & Intervention Center of Excellence, University of Florida, USA; Department of Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, USA.
Burel GoodinDepartment of Psychology, University of Alabama at Birmingham, USA.
Christopher D KingPain Research Center, Cincinnati Children's Hospital Medical Center, USA.
Megan PetrovCollege of Nursing & Health Innovation, Arizona State University, USA.
Emily J BartleyPain Research & Intervention Center of Excellence, University of Florida, USA; Department of Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, USA.
Kimberly T SibillePain Research & Intervention Center of Excellence, University of Florida, USA; Institute on Aging, University of Florida, USA; Department of Aging & Geriatric Research, College of Medicine, University of Florida, USA; Department of Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, USA.
Toni L GloverPain Research & Intervention Center of Excellence, University of Florida, USA; Department of Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, USA.
Matthew S HerbertDepartment of Psychology, University of Alabama at Birmingham, USA.
Hailey W BullsDepartment of Psychology, University of Alabama at Birmingham, USA.
Adriana AddisonDepartment of Psychology, University of Alabama at Birmingham, USA.
Roland StaudDepartment of Medicine, University of Florida, Gainesville, FL, USA.
David ReddenDepartments of Biostatistics and Medicine and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA.
Laurence A BradleyDivision of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA.
Roger B FillingimPain Research & Intervention Center of Excellence, University of Florida, USA; Institute on Aging, University of Florida, USA; Department of Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, USA.
University of Alabama at Birmingham · USUniversity of Florida · USInstitute on Aging · USArizona State University · USCincinnati Children's Hospital Medical Center · US

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Karyn A Esser, Todd Manini · 2007 to 2026
$22.8M
Ethnic Differences in Responses to Painful StimuliR37AG033906 · NIA · UNIVERSITY OF FLORIDA · PI FILLINGIM, ROGER B · 2014 to 2023
$12.9M
UF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2M
UAB Center for Clinical and Translational Science (CCTS) UL1UL1TR000165 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2012 to 2013
$9.6M
Neuroimaging Age-Related Changes i Pain ModulationK01AG048259 · NIA · UNIVERSITY OF FLORIDA · PI CRUZ-ALMEIDA, YENISEL · 2015 to 2019
$831k
Biological Markers of System Burden in Symptomatic Knee OA: A Prospective StudyK23AR062099 · NIAMS · UNIVERSITY OF FLORIDA · PI SIBILLE, KIMBERLY THERESA · 2013 to 2016
$473k
Physiological correlates of endogenous pain modulation in healthy individuals andK99DE022368 · NIDCR · UNIVERSITY OF FLORIDA · PI KING, CHRISTOPHER D · 2012 to 2013
$255k
Adaptability and Resilience in Aging Adults (ARIAA)K99AG052642 · NIA · UNIVERSITY OF FLORIDA · PI BARTLEY, EMILY J. · 2016 to 2017
$233k
NCATS NIH HHS UL1 TR000064NCATS NIH HHS UL1 TR000165NIAMS NIH HHS K23 AR062099NIA NIH HHS K01 AG048259NIA NIH HHS K99 AG052642NIA NIH HHS L30 AG043172NIA NIH HHS P30 AG028740NIA NIH HHS R37 AG033906NIDCR NIH HHS K99 DE022368NIMHD NIH HHS L60 MD010798
6 · The paper itself

Abstract

backgroundKnee pain associated with osteoarthritis is a significant contributor to decreased physical function. Recent evidence supports the inter-individual heterogeneity associated with knee pain presentation, but whether there is similar heterogeneity in physical performance among these individuals has not been previously examined. The aim of the present study was to characterize the variability in physical performance profiles and the pain evoked by their performance (i.e., movement-evoked pain).

methodsIn a secondary analysis of the community-based study Understanding Pain and Limitations in Osteoarthritic Disease (UPLOAD), individuals (n=270) completed functional, pain, psychological, and somatosensory assessments. Hierarchical cluster analysis was used to derive physical function profiles that were subsequently compared across several clinical, psychological and experimental pain measures.

resultsOur results support the hypothesis that among persons with knee OA pain, three different physical performance profiles exist with varying degrees of movement-evoked pain. Even as all three groups experienced moderate to severe levels of spontaneous knee pain, those individuals with the most severe movement-evoked pain and lowest physical functional performance also had the least favorable psychological characteristics along with increased mechanical pain sensitivity and temporal summation.

conclusionsOur findings support the need for the assessment and consideration of movement-evoked pain during physical performance tasks as these have the potential to increase the value of functional and pain assessments clinically. The identification of the mechanisms driving pain burden within homogeneous groups of individuals will ultimately allow for targeted implementation of treatments consistent with a biopsychosocial model of pain.

Indexed as

Independent LivingMotor ActivityPain MeasurementAgedAged, 80 and overAlabamaArthralgiaBiomechanical PhenomenaCluster AnalysisFemaleFloridaHealth StatusHealth Status IndicatorsHumansKnee JointMaleInter-individual variabilityPainPhysical function

Identifiers

PMID28842222
PMCPMC5652068
OpenAlexW2749898093

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.