ArticlePloS one2017
Correlation between ICDAS and histology: Differences between stereomicroscopy and microradiography with contrast solution as histological techniques.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Visual or visual-tactile examination to detect and inform the diagnosis of enamel caries.The Cochrane database of systematic reviews · 2021Pooled it
- Optical Coherence Tomography for Assessing the Severity of Dental Caries: An In Vitro Validation Study.Dentistry journal · 2025Article
- Biochemical Saliva Analysis and Caries Experience In Children With Black Tooth Stain.Oral health & preventive dentistry · 2025Article
- Evaluation of dental caries detection with quantitative light-induced fluorescence in comparison to different field of view devices.Scientific reports · 2022Article
- ICCMS™ root caries lesions stages and their underlying depth towards the pulp: an in vitro study with histologic evaluation.Clinical oral investigations · 2022Article
- Demineralization detection in orthodontics using an ophthalmic optical coherence tomography device equipped with a multicolor fluorescence module.Clinical oral investigations · 2020Article
- Diagnostic Drama. Use of ICDAS II and Fluorescence-Based Intraoral Camera in Early Occlusal Caries Detection: A Clinical Study.International journal of environmental research and public health · 2020Article
- Article
- Natural enamel caries, dentine reactions, dentinal fluid and biofilm.Scientific reports · 2019Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Detection of occlusal caries with visual examination using ICDAS correlates strongly with histology under stereomicroscopy (SM), but dentin aspects under SM are ambiguous regarding mineral content. Thus, our aim was to test two null hypotheses: SM and microradiography result in similar correlations between ICDAS and histology; SM and microradiography result in similar positive (PPV) and negative predictive values (NPV) of ICDAS cut-off 1-2 (scores 0-2 as sound) with histological threshold D3 (demineralization in the inner third of dentin). Occlusal surfaces of extracted permanent teeth (n = 115) were scored using ICDAS. Undemineralized ground sections were histologically scored using both SM without contrast solution and microradiography after immersion in Thoulet's solution 1.47 for 24 h (MRC). Correlation between ICDAS and histology differed from SM (0.782) to MRC (0.511) (p = 0.0002), with a large effect size "q" of 0.49 (95% CI: 0.638/0.338). For ICDAS cut-off 1-2 and D3, PPV from MRC (0.56) was higher than that from SM (0.28) (p< 0.00001; effect size h = 0.81), and NPV from MRC (0.72) was lower than that from SM (1,00) (p < 0.00001; effect size h = 1.58). In conclusion, SM overestimated the correlation between ICDAS and lesion depth, and underestimated the number of occlusal surfaces with ICDAS cut-off 1-2 and deep dentin demineralization.
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