Observational studyCritical care medicine2017
Delirium and Catatonia in Critically Ill Patients: The Delirium and Catatonia Prospective Cohort Investigation.
Observational study in Critical care medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 126 citations in OpenAlex.
- Evidence-based consensus guidelines for the management of catatonia: Recommendations from the British Association for Psychopharmacology.Journal of psychopharmacology (Oxford, England) · 2023Guideline
- Persistent catatonia following epileptic seizures: a case report and systematic literature search.BMC psychiatry · 2018Pooled it
- Recurrent Catatonia in the Setting of Urinary Tract Infection and Medical Comorbidity: A Case Report.Cureus · 2026Article
- The Neuropsychiatric Disturbances of Delirium: A Review of Syndromes and Their Treatment.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026Review
- Electrographic Features of Catatonia With or Without Comorbid Delirium.The Journal of neuropsychiatry and clinical neurosciences · 2026Article
- Lessons on catatonia with or without delirium on the consultation-liaison psychiatry service in a Lebanese tertiary care center: a retrospective chart review of 36 cases of catatonia.BMC psychiatry · 2025Article
- Recognizing Catatonia Beyond Hypokinesis: Features Linked to Underdiagnosis and Training Targets.Journal of clinical medicine · 2025Article
- The Catatonia Quick Screen (CQS): A Rapid Screening Tool for Catatonia in Adult and Pediatric Populations.Acta psychiatrica Scandinavica · 2025Article
- Co-occurrence of Autism, Psychosis and Catatonia: A Scoping Review.Journal of autism and developmental disorders · 2025Article
- Dimensions of Psychosis in Delirious and Catatonic Trauma Critically Ill Patients.Biomarkers in neuropsychiatry · 2025Article
- Electroconvulsive Therapy for Malignant Catatonia: A Case Report in the Intensive Care Unit.Cureus · 2025Article
- ECT and Delirium: Literature Review and a Pediatric Case Report.Current psychiatry reports · 2025Review
- Catatonia in ICD-11.BMC psychiatry · 2025Review
- What Internists and Neurologists Know and Think About Catatonia.The primary care companion for CNS disorders · 2025Article
- A Prospective Nested Case-Control Study of Risk Factors for Postoperative Delirium in Elderly Patients with Colorectal Cancer.Clinical interventions in aging · 2025Article
- Construction and validation of a machine learning-based nomogram model for predicting pneumonia risk in patients with catatonia: a retrospective observational study.Frontiers in psychiatry · 2025Article
- Relevance of Preoperative Cognitive Impairment for Predicting Postoperative Delirium in Surgical Medicine: A Prospective Cohort Study.Geriatrics (Basel, Switzerland) · 2024Article
- Clinical Reasoning: A 17-Year-Old Adolescent Boy With New Altered Mental Status in the Pediatric Intensive Care Unit.Neurology · 2024Article
- Catatonia.Nature reviews. Disease primers · 2024Review
- Delirium in psychiatric settings: risk factors and assessment tools in patients with psychiatric illness: a scoping review.BMC nursing · 2024Article
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesCatatonia, a condition characterized by motor, behavioral, and emotional changes, can occur during critical illness and appear as clinically similar to delirium, yet its management differs from delirium. Traditional criteria for medical catatonia preclude its diagnosis in delirium. Our objective in this investigation was to understand the overlap and relationship between delirium and catatonia in ICU patients and determine diagnostic thresholds for catatonia.
designConvenience cohort, nested within two ongoing randomized trials.
settingSingle academic medical center in Nashville, TN. PATIENTS: We enrolled 136 critically ill patients on mechanical ventilation and/or vasopressors, randomized to two usual care sedation regimens. MEASUREMENTS AND MAIN
resultsPatients were assessed for delirium and catatonia by independent and masked personnel using Confusion Assessment Method for the ICU and the Bush Francis Catatonia Rating Scale mapped to Diagnostic Statistical Manual 5 criterion A for catatonia. Of 136 patients, 58 patients (43%) had only delirium, four (3%) had only catatonia, 42 (31%) had both, and 32 (24%) had neither. In a logistic regression model, more catatonia signs were associated with greater odds of having delirium. For example, patient assessments with greater than or equal to three Diagnostic Statistical Manual 5 symptoms (75th percentile) had, on average, 27.8 times the odds (interquartile range, 12.7-60.6) of having delirium compared with patient assessments with zero Diagnostic Statistical Manual 5 criteria (25th percentile) present (p < 0.001). A cut-off of greater than or equal to 4 Bush Francis Catatonia Screening Instrument items was both sensitive (91%; 95% CI, 82.9-95.3) and specific (91%; 95% CI, 87.6-92.9) for Diagnostic Statistical Manual 5 catatonia.
conclusionsGiven that about one in three patients had both catatonia and delirium, these data prompt reconsideration of Diagnostic Statistical Manual 5 criteria for "Catatonic Disorder Due to Another Medical Condition" that preclude diagnosing catatonia in the presence of delirium.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.