Evidence map›Paper›PMID 28841618›Full record

ArticlePlastic and reconstructive surgery2017

Intelligence and Academic Achievement of Adolescents with Craniofacial Microsomia.

Matthew L Speltz, Erin R Wallace, Brent R Collett, Carrie L Heike, Daniela V Luquetti, Martha M Werler

Open access · greenAbstract read
In one paragraph

Article in Plastic and reconstructive surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Establishing an International Interdisciplinary Research Network in Craniofacial Microsomia: The CARE Program.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Psychosocial and Health-Related Experiences of Individuals With Microtia and Craniofacial Microsomia and Their Families: Narrative Review Over 2 Decades.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2023
    Review
  8. Article
  9. Cognitive, Motor, and Language Development of Preschool Children With Craniofacial Microsomia.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2021
    Article
  10. [Obstructive sleep apnea in microtia children with maxillofacial dysostosis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021
    Review
  11. Behavioral Adjustment of Preschool Children With and Without Craniofacial Microsomia.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2021
    Article
  12. Article
  13. Methods and Challenges in a Cohort Study of Infants and Toddlers With Craniofacial Microsomia: The Clock Study.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2019
    Article
  14. Article
  15. Observational
  16. Article
  17. Caregiver Perspectives on School Participation Among Students With Craniofacial Microsomia.The American journal of occupational therapy : official publication of the American Occupational Therapy Association
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Matthew L SpeltzSeattle, Wash.; and Boston, Mass.
Erin R WallaceSeattle, Wash.; and Boston, Mass.
Brent R CollettSeattle, Wash.; and Boston, Mass.
Carrie L HeikeSeattle, Wash.; and Boston, Mass.
Daniela V LuquettiSeattle, Wash.; and Boston, Mass.
Martha M WerlerSeattle, Wash.; and Boston, Mass.
Virginia Mason Medical Center · US

Funding

Hemifacial Microsomia: Psychosocial and Other SequelaeR01DE011939 · NIDCR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WERLER, MARTHA M. · 1997 to 2015
$7.3M
NIDCR NIH HHS R01 DE011939
6 · The paper itself

Abstract

backgroundThe authors compared the IQ and academic achievement of adolescents with craniofacial microsomia (cases) and unaffected children (controls). Among cases, the authors analyzed cognitive functioning by facial phenotype.

methodsThe authors administered standardized tests of intelligence, reading, spelling, writing, and mathematics to 142 cases and 316 controls recruited from 26 cities across the United States and Canada. Phenotypic classification was based on integrated data from photographic images, health history, and medical chart reviews. Hearing screens were conducted for all participants.

resultsAfter adjustment for demographics, cases' average scores were lower than those of controls on all measures, but the magnitude of differences was small (standardized effect sizes, -0.01 to -0.3). There was little evidence that hearing status modified case-control group differences (Wald p > 0.05 for all measures). Twenty-five percent of controls and 38 percent of cases were classified as having learning problems (adjusted OR, 1.5; 95 percent CI, 0.9 to 2.4). Comparison of cases with and without learning problems indicated that those with learning problems were more likely to be male, Hispanic, and to come from lower income, bilingual families. Analyses by facial phenotype showed that case-control group differences were largest for cases with both microtia and mandibular hypoplasia (effect sizes, -0.02 to -0.6).

conclusionsThe highest risk of cognitive-academic problems was observed in patients with combined microtia and mandibular hypoplasia. Developmental surveillance of this subgroup is recommended, especially in the context of high socioeconomic risk and bilingual families. Given the early stage of research on craniofacial microsomia and neurodevelopment, replication of these findings is needed. CLINICAL QUESTION/LEVEL OF EVIDENCE: Risk, II.

Indexed as

Educational StatusIntelligenceAdolescentCanadaCase-Control StudiesChildFemaleGoldenhar SyndromeHearingHumansLearning DisabilitiesMalePhenotypeRegression Analysis

Identifiers

PMID28841618
PMCPMC5657387
OpenAlexW2745979781

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.