ArticleVirology2017
Detection and characterization of an H4N6 avian-lineage influenza A virus in pigs in the Midwestern United States.
Article in Virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 38 citations in OpenAlex.
- Article
- Adaptive mutations in HA of avian H9N2 influenza viruses facilitate their transmission to swine.Veterinary research · 2025Article
- Ecological drivers of evolution of swine influenza in the United States: a review.Emerging microbes & infections · 2025Review
- Recent advances in lateral flow devices and point-of-care diagnostics for highly pathogenic avian influenza A viruses.Journal of virology · 2025Review
- Epidemiological, phylogenetic, and pathogenicity analysis of H4 subtype avian influenza viruses in China, 2011-2022.Virologica Sinica · 2025Article
- Emerging threats of HPAI H5N1 clade 2.3.4.4b in swine: knowledge gaps and the imperative for a One Health approach.Frontiers in veterinary science · 2025Review
- Spatial patterns of influenza A virus spread across compartments in commercial swine farms in the United States.Emerging microbes & infections · 2024Article
- Evolution of influenza A viruses in exhibition swine and transmission to humans, 2013-2015.Zoonoses and public health · 2024Article
- Cross-Species Transmission Potential of H4 Avian Influenza Viruses in China: Epidemiological and Evolutionary Study.Viruses · 2024Article
- Genetic and Biological Characteristics of Duck-Origin H4N6 Avian Influenza Virus Isolated in China in 2022.Viruses · 2024Article
- Geographical distribution and evolutionary dynamics of H4Nx avian influenza viruses.Frontiers in microbiology · 2024Article
- Review
- Are pigs overestimated as a source of zoonotic influenza viruses?Porcine health management · 2022Review
- Review of genome sequencing technologies in molecular characterization of influenza A viruses in swine.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022Article
- Effect of SerialJournal of veterinary research · 2022Article
- Deciphering transmission dynamics and spillover of avian influenza viruses from avian species to swine populations globally.Virus genes · 2021Article
- Triple reassortment increases compatibility among viral ribonucleoprotein genes of contemporary avian and human influenza A viruses.PLoS pathogens · 2021Article
- A novel reassortant avian influenza H4N6 virus isolated from an environmental sample during a surveillance in Maharashtra, India.The Indian journal of medical research · 2021Article
- Genomic Evidence for Sequestration of Influenza A Virus Lineages in Sea Duck Host Species.Viruses · 2021Article
- The epidemiology of swine influenza.Animal diseases · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
H4Nx viruses were reported in swine in Canada and China, but had not been recognized in swine in the USA. In late 2015, an avian-origin H4N6 influenza A virus was isolated from pigs in the United States during a routine diagnostic investigation of clinical respiratory disease in the herd. Serological analysis from additional pigs at the farm and other pigs within the swine production system indicated that the virus did not efficiently transmit from pig-to-pig and the mode of transmission to swine could not be determined. The isolate was characterized at the molecular level and the pathogenesis and transmission was experimentally evaluated in pigs. Although the virus replicated in the lungs of pigs and caused mild pulmonary lesions, there was no evidence of replication in the upper respiratory tract or transmission to indirect contacts, supporting the findings on the farm.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.