Evidence map›Paper›PMID 28840860›Full record

ArticleCell research2017

tsRNAs: new players in mammalian retrotransposon control.

Yunfang Zhang, Junchao Shi, Qi Chen

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  12. Transfer RNA-Derived Small RNAs: Another Layer of Gene Regulation and Novel Targets for Disease Therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2020
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Yunfang ZhangDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, NV 89512, USA.
Junchao ShiDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, NV 89512, USA.
Qi ChenDepartment of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, NV 89512, USA.

Funding

Sperm tsRNAs/rsRNAs and their RNA modifications in diet-induced epigenetic inheritanceR01HD092431 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Qi Chen, David S Milstone · 2017 to 2026
$3.5M
NICHD NIH HHS R01 HD092431
6 · The paper itself

Abstract

A recent study led by Professor Rob Martienssen in Cell showed that 3'-tRNA-derived small RNAs can suppress long terminal repeat retrotransposon activity in mammalian cells by mechanisms independent of DNA-associated epigenetic marks, suggesting how the genome may defend itself from retrotransposon invasion during epigenetic reprogramming.

Indexed as

RetroelementsTerminal Repeat SequencesAnimalsMammalsRNARNA, TransferRetroelementsRNARNA, Transfer

Identifiers

PMID28840860
PMCPMC5674153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.