Evidence map›Paper›PMID 28840831›Full record

ArticleBioMedicine2017

Fluvastatin use and risk of acute pancreatitis: a population-based case-control study in Taiwan.

Kuan-Fu Liao, Po-Tsung Huang, Ching-Chun Lin, Cheng-Li Lin, Shih-Wei Lai

Abstract read
In one paragraph

Article in BioMedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Observational
  2. Article
  3. Association between allopurinol use and hepatocellular carcinoma in a case-control study in Taiwan.European journal of hospital pharmacy : science and practice · 2019
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  5. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kuan-Fu LiaoCollege of Medicine, Tzu Chi University, Hualien 970, Taiwan - Department of Internal Medicine, Taichung Tzu Chi General Hospital, Taichung 427, Taiwan - Graduate Institute of Integrated Medicine, China Medical University, Taichung 404, Taiwan.
Po-Tsung HuangDepartment of Family Medicine, China Medical University Hospital, Taichung 404, Taiwan.
Ching-Chun LinDepartment of Family Medicine, China Medical University Hospital, Taichung 404, Taiwan.
Cheng-Li LinCollege of Medicine, China Medical University, Taichung 404, Taiwan - Management Office for Health Data, China Medical University Hospital, Taichung 404, Taiwan.
Shih-Wei LaiCollege of Medicine, China Medical University, Taichung 404, Taiwan - Department of Family Medicine, China Medical University Hospital, Taichung 404, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to examine the association between fluvastatin use and acute pancreatitis in Taiwan.

methodsUsing the database from the Taiwan National Health Insurance (NHI) Program, we designed a case-control study which consisted of 3501 individuals aged 20-84 with new at-the-time diagnoses acute pancreatitis as the case group and 8373 randomly selected individuals without acute pancreatitis as the control group during the period of 1998-2011. Both groups were matched for sex, age, and index year of being diagnosed with acute pancreatitis. "Current use" of fluvastatin was defined as individuals whose last remaining tablet of fluvastatin was noted ≤ 7 days before the date of their being diagnosed with acute pancreatitis. "Late use" of fluvastatin was defined as individuals whose last remaining tablet of fluvastatin was noted within 8-30 days before the date of their being diagnosed with acute pancreatitis. "No use" of fluvastatin was defined as individuals who had never had a fluvastatin prescription. The odds ratio (OR) and 95% confidence interval (CI) for acute pancreatitis associated with fluvastatin use was examined using a multivariable unconditional logistic regression analysis.

resultsAfter adjustment for potential confounders, the multivariable analysis showed that the adjusted ORs of acute pancreatitis were 1.17 for individuals with "current use" of fluvastatin (95% CI 0.69, 1.97) and 1.82 for individuals with "late use" of fluvastatin (95% CI 0.41, 8.19), but there was no statistical significance when compared with individuals with "no use" of fluvastatin.

conclusionsIn this this study, no association was detected between fluvastatin use and acute pancreatitis.

Identifiers

PMID28840831
PMCPMC5571662

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.