ReviewMicrobiology spectrum2017
Ecological Therapeutic Opportunities for Oral Diseases.
Review in Microbiology spectrum, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Microbial signatures in human periodontal disease: a metatranscriptome meta-analysis.Frontiers in microbiology · 2024Pooled it
- Are dairy products containing probiotics beneficial for oral health? A systematic review and meta-analysis.Clinical oral investigations · 2018Pooled it
- Effect of a Short-Term Intervention withInternational journal of environmental research and public health · 2022Trial
- Reduction of Streptococcus mutans by probiotic milk: a multicenter randomized controlled trial.Clinical oral investigations · 2020Trial
- A pilot study to assess oral colonization and pH buffering by the probiotic Streptococcus dentisani under different dosing regimes.Odontology · 2020Trial
- Modulating Oral Microbiota to Prevent Dental Caries: A Microbial Ecology Approach.Dentistry journal · 2026Review
- Periodontitis and Pancreatic Cancer Risk: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis.Journal of clinical medicine · 2026Review
- Salivary proteins, proteases, and disease pathophysiology in oral health and precision diagnostics: a narrative review.Frontiers in dental medicine · 2026Review
- The multifaceted role of oral microbiota-host interactions in oral submucous fibrosis: from pathogenic mechanisms to microecological regulation therapies.Frontiers in microbiology · 2026Review
- The Effect of Chlorhexidine Mouthwashes on the Microbiota Associated with Peri-Implantitis Lesions: A Pilot Study.Antibiotics (Basel, Switzerland) · 2025Article
- Altered oral health and microbiota in drug-free patients with schizophrenia.BMC psychiatry · 2025Observational
- Review
- A bibliometric and visualized in oral microbiota and cancer research from 2013 to 2022.Discover oncology · 2024Article
- The Evolving Microbiome of Dental Caries.Microorganisms · 2024Review
- Inhibitory effect of helium cold atmospheric plasma on cariogenic biofilms.Journal of oral microbiology · 2024Article
- Mechanism of Action ofAntibiotics (Basel, Switzerland) · 2023Article
- The Potential Value of Probiotics after Dental Implant Placement.Microorganisms · 2023Review
- Beneficial modulation of human health in the oral cavity and beyond using bacteriocin-like inhibitory substance-producing streptococcal probiotics.Frontiers in microbiology · 2023Review
- Oral microbiota dysbiosis accelerates the development and onset of mucositis and oral ulcers.Frontiers in microbiology · 2023Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The three main oral diseases of humans, that is, caries, periodontal diseases, and oral candidiasis, are associated with microbiome shifts initiated by changes in the oral environment and/or decreased effectiveness of mucosal immune surveillance. In this review, we discuss the role that microbial-based therapies may have in the control of these conditions. Most investigations on the use of microorganisms for management of oral disease have been conducted with probiotic strains with some positive but very discrete clinical outcomes. Other strategies such as whole oral microbiome transplantation or modification of community function by enrichment with health-promoting indigenous oral strains may offer more promise, but research in this field is still in its infancy. Any microbial-based therapeutics for oral conditions, however, are likely to be only one component within a holistic preventive strategy that should also aim at modification of the environmental influences responsible for the initiation and perpetuation of microbiome shifts associated with oral dysbiosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.