Evidence map›Paper›PMID 28840515›Full record

ReviewCurrent cardiology reports2017

High-Sensitivity Cardiac Troponin for the Diagnosis of Patients with Acute Coronary Syndromes.

Vlad C Vasile, Allan S Jaffe

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Observational
  3. The HEART score has less utility with high sensitivity troponin.Frontiers in cardiovascular medicine · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Impact of a rapid high-sensitivity troponin pathway on patient flow in an urban emergency department.Journal of the American College of Emergency Physicians open · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Vlad C VasileDivision of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Gonda 5, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Allan S JaffeDivision of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Gonda 5, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. Jaffe.Allan@Mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewHigh-sensitivity cardiac troponin (hscTn) assays are replacing the older-generation assays used to detect myocardial injury because they have improved analytical sensitivity and lead to a more rapid diagnosis of acute myocardial infarction (AMI) and enhanced risk stratification in patients with non-ST elevation acute coronary syndromes (NSTE-ACS). This review focuses on advantages and difficulties of using hscTn as diagnostic and prognostic tools in acute coronary syndromes (ACS). RECENT

findingsThe newer assays have a lower specificity for AMI as compared to conventional assays, potentially leading to an increased number of unwarranted hospitalizations and amplified cost unless how to use these assays appropriately is appreciated. Several approaches can increase the specificity of the high sensitivity assays. This review will present the current literature data regarding the use of hscTn assays and will focus on modalities used to increase the specificity, as well as the advantages and pitfalls of using the high sensitivity approach in clinical practice.

Indexed as

Acute Coronary SyndromeBiomarkersHumansMyocardial InfarctionNon-ST Elevated Myocardial InfarctionPrognosisSensitivity and SpecificityTroponinBiomarkersTroponinAcute coronary syndromesDiagnosisHigh sensitivity cardiac troponinPrognosis

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.