Evidence map›Paper›PMID 28840482›Full record

ArticleMolecular neurobiology2018

Nanodelivery of Cerebrolysin and Rearing in Enriched Environment Induce Neuroprotective Effects in a Preclinical Rat Model of Parkinson's Disease.

C Requejo, J A Ruiz-Ortega, H Cepeda, A Sharma, H S Sharma, A Ozkizilcik, R Tian, H Moessler, L Ugedo, J V Lafuente

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Enriched environment as a nonpharmacological neuroprotective strategy.Experimental biology and medicine (Maywood, N.J.) · 2023
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 5 countries.

C RequejoLaNCE, Department of Neuroscience, University of the Basque Country (UPV/EHU), Leioa, Vizcaya, Spain. catalina.requejo@ehu.eus.
J A Ruiz-OrtegaDepartment of Pharmacology, University of the Basque Country (UPV/EHU), Leioa, Vizcaya, Spain.
H CepedaLaNCE, Department of Neuroscience, University of the Basque Country (UPV/EHU), Leioa, Vizcaya, Spain.
A SharmaInternational Experimental CNS Injury & Repair, Uppsala University, Uppsala, Sweden.
H S SharmaLaNCE, Department of Neuroscience, University of the Basque Country (UPV/EHU), Leioa, Vizcaya, Spain.
A OzkizilcikDepartment of Biomedical Engineering, University of Arkansas, Fayetteville, AR, USA.
R TianDepartment of Biomedical Engineering, University of Arkansas, Fayetteville, AR, USA.
H MoesslerDrug Discovery & Develop, Ever Neuro Pharma, Oberburgau, Austria.
L UgedoDepartment of Pharmacology, University of the Basque Country (UPV/EHU), Leioa, Vizcaya, Spain.
J V LafuenteLaNCE, Department of Neuroscience, University of the Basque Country (UPV/EHU), Leioa, Vizcaya, Spain.
University of the Basque Country · ESUniversity of Arkansas at Fayetteville · USEVER Neuro Pharma (Austria) · ATUniversidad Autónoma de Chile · CLUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rearing in enriched environment (EE) improves the recuperation in animal models of Parkinson's disease (PD). Administration of TiO

Indexed as

Disease Models, AnimalEnvironmentAmino AcidsAnimalsDrug Delivery SystemsMaleNanoparticlesNeuroprotective AgentsParkinsonian DisordersRatsRats, Sprague-DawleyAmino AcidscerebrolysinNeuroprotective Agents6-OHDAEnriched environmentNanowired cerebrolysinNeuroprotectionParkinson’s diseasePreclinical stage

Identifiers

PMID28840482
OpenAlexW2748556992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.