Evidence map›Paper›PMID 28840457›Full record

ReviewCurrent psychiatry reports2017

VA's National PTSD Brain Bank: a National Resource for Research.

Matthew J Friedman, Bertrand R Huber, Christopher B Brady, Robert J Ursano, David M Benedek, Neil W Kowall, Ann C McKee, Traumatic Stress Brain Research Group

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current psychiatry reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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  5. Article
  6. Trauma Exposure, PTSD, and Methylation of the Blood Brain Barrier Claudin-5 Gene.medRxiv : the preprint server for health sciences · 2025
    Article
  7. A Multivariate Genomic Investigation of the Externalizing Spectrum and Suicide Risk.medRxiv : the preprint server for health sciences · 2025
    Article
  8. Brain donation rules in Italy and worldwide: overview of a cutting-edge topic for human brain research.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Matthew J FriedmanNational Center for PTSD, VA Medical Center, U.S. Department of Veterans Affairs, 215 North Main Street, White River Junction, VT, 05009, USA. Matthew.J.Friedman@Dartmouth.edu.
Bertrand R HuberVA Boston Healthcare System, Boston University School of Medicine, 150 South Huntington Avenue, Building 1, Room 12C6, Boston, MA, 02130, USA.
Christopher B BradyVA Boston Healthcare System, Boston University School of Medicine, 150 South Huntington Avenue, Building 1, Room 12C6, Boston, MA, 02130, USA.
Robert J UrsanoCenter for the Study of Traumatic Stress (CSTS), Department of Psychiatry, Uniformed Services University of the Health Sciences, School of Medicine, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA.
David M BenedekCenter for the Study of Traumatic Stress (CSTS), Department of Psychiatry, Uniformed Services University of the Health Sciences, School of Medicine, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA.
Neil W KowallVA Boston Healthcare System, Boston University School of Medicine, 150 South Huntington Avenue, Building 1, Room 12C6, Boston, MA, 02130, USA.
Ann C McKeeVA Boston Healthcare System, Boston University School of Medicine, 150 South Huntington Avenue, Building 1, Room 12C6, Boston, MA, 02130, USA.
Traumatic Stress Brain Research Group
Boston University · USUniformed Services University of the Health Sciences · USVA Boston Healthcare System · USUnited States Department of Veterans Affairs · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The National PTSD Brain Bank (NPBB) is a brain tissue biorepository established to support research on the causes, progression, and treatment of PTSD. It is a six-part consortium led by VA's National Center for PTSD with participating sites at VA medical centers in Boston, MA; Durham, NC; Miami, FL; West Haven, CT; and White River Junction, VT along with the Uniformed Services University of Health Sciences. It is also well integrated with VA's Boston-based brain banks that focus on Alzheimer's disease, ALS, chronic traumatic encephalopathy, and other neurological disorders. This article describes the organization and operations of NPBB with specific attention to: tissue acquisition, tissue processing, diagnostic assessment, maintenance of a confidential data biorepository, adherence to ethical standards, governance, accomplishments to date, and future challenges. Established in 2014, NPBB has already acquired and distributed brain tissue to support research on how PTSD affects brain structure and function.

Indexed as

United States Department of Veterans AffairsBiomedical ResearchBrainHumansStress Disorders, Post-TraumaticTissue BanksUnited StatesBrain bankingConfidential data biorepositoryDiagnostic assessmentInformed consentNeuropathologyPosttraumatic stress disorder

Identifiers

PMID28840457
OpenAlexW2749156539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.