Evidence map›Paper›PMID 28840456›Full record

Observational studyJournal of thrombosis and thrombolysis2017

Effects of statin therapy on platelet reactivity after percutaneous coronary revascularization in patients with acute coronary syndrome.

Anna Toso, Stefano De Servi, Mario Leoncini, Dominick J Angiolillo, Paolo Calabrò, Federico Piscione, Marco Cattaneo, Diego Maffeo, Antonio Bartorelli, Cataldo Palmieri and 8 more

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of thrombosis and thrombolysis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 12 institutions in 3 countries.

Anna TosoCardiology Division, Santo Stefano Hospital, Via Suor Niccolina infermiera, 22, Prato, Italy. anna.toso@libero.it.ORCID http://orcid.org/0000-0002-8404-3993
Stefano De ServiMultimedica, IRCCS, Milano, Italy.
Mario LeonciniCardiology Division, Santo Stefano Hospital, Via Suor Niccolina infermiera, 22, Prato, Italy.
Dominick J AngiolilloDivision of Cardiology, Department of Medicine, University of Florida, Jacksonville, FL, USA.
Paolo CalabròDepartment of Cardiothoracic and Respiratory Sciences, Università degli Studi della Campania "Luigi Vanvitelli", Napoli, Italy.
Federico PiscioneHeart Department, SS. Giovanni di Dio e Ruggi d'Aragona Hospital, Salerno, Italy.
Marco CattaneoDivision of Medicine 3, ASST Santi Paolo e Carlo, Department of Health Science, University of Milano, Milano, Italy.
Diego MaffeoCardiology Unit, Istituto clinico Fondazione Poliambulanza, Brescia, Italy.
Antonio BartorelliMonzino Heart Center, IRCCS, Milano, Italy.
Cataldo PalmieriDepartment of Interventional Cardiology, Heart Hospital, Massa, Italy.
Marco De CarloCatheterization Laboratory, Azienda Ospedaliero-Universitaria di Pisa, Pisa, Italy.
Davide CapodannoFerrarotto Hospital, University of Catania, Catania, Italy.
Philippe GenereuxThe Cardiovascular Research Foundation, New York, NY, USA.
Francesco BellandiCardiology Division, Santo Stefano Hospital, Via Suor Niccolina infermiera, 22, Prato, Italy.
Chiara BarozziCardiovascular Department, Policlinico S. Orsola, Bologna, Italy.
Luciana TomasiCardiovascular Department, Policlinico S. Orsola, Bologna, Italy.
Diego Della RivaCardiovascular Department, Policlinico S. Orsola, Bologna, Italy.
Tullio PalmeriniCardiovascular Department, Policlinico S. Orsola, Bologna, Italy.
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITAzienda Ospedaliera Universitaria Pisana · ITCentro Cardiologico Monzino · ITFondazione Poliambulanza Istituto Ospedaliero · ITMorristown Medical Center · USMultiMedica · ITOspedale di Prato Santo Stefano · ITOspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Catania · ITUniversity of Florida · USUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Statin use is associated with enhanced pharmacodynamic response to clopidogrel in patients with stable coronary artery disease undergoing percutaneous coronary intervention (PCI). However, the impact of statin therapy on clopidogrel response profiles in patients with acute coronary syndrome (ACS) undergoing PCI has not been established and represents the objective of this investigation. On-treatment P2Y

Indexed as

Percutaneous Coronary InterventionAcute Coronary SyndromeAgedAged, 80 and overClopidogrelHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMiddle AgedPlatelet ActivationTiclopidineClopidogrelHydroxymethylglutaryl-CoA Reductase InhibitorsTiclopidineAcute coronary syndromeClopidogrelHigh platelet reactivityPharmacodynamicsStatins

Identifiers

PMID28840456
OpenAlexW2750459267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.