Evidence map›Paper›PMID 28840444›Full record

ReviewCurrent osteoporosis reports2017

Effects of Excessive Dietary Phosphorus Intake on Bone Health.

Colby J Vorland, Elizabeth R Stremke, Ranjani N Moorthi, Kathleen M Hill Gallant

Open access · greenAbstract readReview
In one paragraph

Review in Current osteoporosis reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 123 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Phosphate homeostasis and endocrine regulators.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Colby J VorlandDepartment of Nutrition Science, Purdue University, 700 West State Street, West Lafayette, IN, 47907, USA.
Elizabeth R StremkeDepartment of Nutrition Science, Purdue University, 700 West State Street, West Lafayette, IN, 47907, USA.
Ranjani N MoorthiDepartment of Medicine-Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, USA.
Kathleen M Hill GallantDepartment of Nutrition Science, Purdue University, 700 West State Street, West Lafayette, IN, 47907, USA. hillgallant@purdue.edu.
Indiana University – Purdue University Indianapolis · USState Street (United States) · US

Funding

Longitudinal Assessment of Skeletal Muscle Physiology in Dialysis PatientsK23DK102824 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI MOORTHI, RANJANI N. · 2015 to 2019
$892k
Phosphorus Absorption and Balance in Normal Physiology and Chronic Kidney DiseaseK01DK102864 · NIDDK · UNIVERSITY OF MINNESOTA · PI GALLANT, KATHLEEN M HILL · 2015 to 2019
$692k
NIDDK NIH HHS K01 DK102864NIDDK NIH HHS K23 DK102824
6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to provide an overview of dietary phosphorus, its sources, recommended intakes, and its absorption and metabolism in health and in chronic kidney disease and to discuss recent findings in this area with a focus on the effects of inorganic phosphate additives in bone health. RECENT

findingsRecent findings show that increasing dietary phosphorus through inorganic phosphate additives has detrimental effects on bone and mineral metabolism in humans and animals. There is new data supporting an educational intervention to limit phosphate additives in patients with chronic kidney disease to control serum phosphate. The average intake of phosphorus in the USA is well above the recommended dietary allowance. Inorganic phosphate additives, which are absorbed at a high rate, account for a substantial and likely underestimated portion of this excessive intake. These additives have negative effects on bone metabolism and present a prime opportunity to lower total phosphorus intake in the USA. Further evidence is needed to confirm whether lowering dietary phosphorus intake would have beneficial effects to improve fracture risk.

Indexed as

Bone and BonesBone Diseases, MetabolicCalcium, DietaryCarbonated BeveragesHumansPhosphatesPhosphorus, DietaryRenal Insufficiency, ChronicCalcium, DietaryPhosphatesPhosphorus, DietaryBoneNutritionPhosphate additivesPhosphorus

Identifiers

PMID28840444
PMCPMC5693714
OpenAlexW2746974207

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.