Evidence map›Paper›PMID 28840304›Full record

ReviewCurrent genetics2018

MybA, a new player driving survival of the conidium of the human pathogen Aspergillus fumigatus.

Özlem Sarikaya Bayram, Jean Paul Latgé, Özgür Bayram

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Temperature duringbioRxiv : the preprint server for biology · 2026
    Article
  3. Genome Sequencing and Metabolic Potential Analysis ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Özlem Sarikaya BayramBiology Department, Maynooth University, Maynooth, Co. Kildare, Ireland.
Jean Paul LatgéUnité des Aspergillus, Institut Pasteur, 75015, Paris, France.
Özgür BayramBiology Department, Maynooth University, Maynooth, Co. Kildare, Ireland. ozgur.bayram@mu.ie.ORCID http://orcid.org/0000-0002-0283-5322
National University of Ireland, Maynooth · IEInstitut Pasteur · FR

Funding

Irish Research Council for Science, Engineering and Technology GOIPD/2014/178Science Foundation Ireland 13/CDA/2142
6 · The paper itself

Abstract

Aspergillus fumigatus is an opportunistic human pathogen that causes various complications in patients with a weakened immune system functions. Asexual spores of A. fumigatus are responsible for initiation of aspergillosis. Long-term viability and proper germination of dormant conidia depend on trehalose accumulation, which protect the spores against thermal and oxidative stress. A putative Myb transcription factor, MybA has been recently found to be responsible for a variety of physiological and molecular roles ranging from conidiation, spore viability, trehalose accumulation, cell wall integrity and protection against reactive oxygen species. In this perspective review, we discuss the recent findings of MybA and its overlapping functions with the other regulators of conidia viability and trehalose accumulation. Therefore, the aim of this perspective is to raise interesting and stimulating questions on the molecular functions of MybA in conidiation and trehalose biogenesis and to question its genetic and physical interactions with the other regulators of conidial viability.

Indexed as

Aspergillus fumigatusEnvironmentFungal ProteinsGene-Environment InteractionHost-Pathogen InteractionsHumansMicrobial ViabilitySpores, FungalTranscription FactorsFungal ProteinsTranscription FactorsAspergillus fumigatusAtfACell wallMybASpore viabilityVelB-VosAWetA

Identifiers

PMID28840304
OpenAlexW2750155781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.