Evidence map›Paper›PMID 28840280›Full record

ArticleAbdominal radiology (New York)2018

Comparison of quantitative apparent diffusion coefficient parameters with prostate imaging reporting and data system V2 assessment for detection of clinically significant peripheral zone prostate cancer.

Elmira Hassanzadeh, Francesco Alessandrino, Olutayo I Olubiyi, Daniel I Glazer, Robert V Mulkern, Andriy Fedorov, Clare M Tempany, Fiona M Fennessy

Open access · greenAbstract readComparative Study
In one paragraph

Article in Abdominal radiology (New York), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Elmira HassanzadehDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Francesco AlessandrinoDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA. falessandrino@bwh.harvard.edu.ORCID 0000-0002-1681-1284
Olutayo I OlubiyiDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Daniel I GlazerDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Robert V MulkernDepartment of Radiology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA, USA.
Andriy FedorovDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Clare M TempanyDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Fiona M FennessyDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Brigham and Women's Hospital · USBoston Children's Hospital · US

Funding

Image Guided Therapy Center - Ultrasound-based sensor system for the monitoring of COVID-19 patientsP41EB015898 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI TEMPANY, CLARE M · 2012 to 2021
$18.9M
Multidisciplinary Training in Image-Guided TherapyR25CA089017 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI FENNESSY, FIONA · 2001 to 2017
$7.8M
Quantitiative MRI of prostate cancer as a biomarker and guide for treatmentU01CA151261 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI FENNESSY, FIONA · 2010 to 2014
$1.8M
NCI NIH HHS R25 CA089017NCI NIH HHS U01 CA151261NIBIB NIH HHS P41 EB015898
6 · The paper itself

Abstract

purposeTo compare diagnostic performance of PI-RADSv2 with ADC parameters to identify clinically significant prostate cancer (csPC) and to determine the impact of csPC definitions on diagnostic performance of ADC and PI-RADSv2.

methodsWe retrospectively identified treatment-naïve pathology-proven peripheral zone PC patients who underwent 3T prostate MRI, using high b-value diffusion-weighted imaging from 2011 to 2015. Using 3D slicer, areas of suspected tumor (T) and normal tissue (N) on ADC (b = 0, 1400) were outlined volumetrically. Mean ADC

resultsEighty five cases met eligibility requirements. Diagnostic performances (AUC) in identifying csPC using three definitions were: (A) ADC

conclusionsWhen csPC was defined by GS, ADC parameters provided better csPC discrimination than PI-RADSv2, with ADC

Indexed as

AdultAgedDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingHumansMaleMiddle AgedProstateProstatic NeoplasmsRetrospective StudiesSensitivity and SpecificityApparent diffusion coefficientDiffusion-weighted imagingGleason scoreMagnetic resonance imagingPI-RADSv2Prostate cancer

Identifiers

PMID28840280
PMCPMC5826788
OpenAlexW2745469378

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.