Evidence map›Paper›PMID 28840259›Full record

ArticleHNO2018

Treatment outcomes of recurrent respiratory papillomatosis : Retrospective analysis of juvenile and adult cases.

V-A Papaioannou, A Lux, S Voigt-Zimmermann, C Arens

Abstract read
PubMed Publisher
In one paragraph

Article in HNO, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Aspiration pneumonia as a complication of recurrent esophageal strictures in a patient with respiratory papillomatosis.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2024
    Article
  4. Diode Laser for Juvenile Recurrent Respiratory Papillomatosis: A Case Series of 13 Patients.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  5. Adult-onset Recurrent Respiratory Papillomatosis at a South African Referral Hospital.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  6. Review
  7. [Research progress in the adjunct therapy of recurrent respiratory papillomatosis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2020
    Review
  8. [Distribution of juvenile laryngeal papilloma in different stages].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2020
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

V-A PapaioannouDepartment of Otorhinolaryngology, Magdeburg University Hospital, Leipziger Straße 44, 39120, Magdeburg, Germany. vasiliki-anna.papaioannou@med.ovgu.de.
A LuxInstitute for biometry and medical informatics, Magdeburg University Hospital, Magdeburg, Germany.
S Voigt-ZimmermannDepartment of Otorhinolaryngology, Magdeburg University Hospital, Leipziger Straße 44, 39120, Magdeburg, Germany.
C ArensDepartment of Otorhinolaryngology, Magdeburg University Hospital, Leipziger Straße 44, 39120, Magdeburg, Germany.
University Hospital Magdeburg · DEUniversity Hospital Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecurrent respiratory papillomatosis (RRP) is a rare, chronic disease of viral etiology which is characterized by multiple, recurrent growth of papillomas in the aerodigestive tract. MATERIALS AND

methodsThe surgical outcomes and the recurrence rates of 106 patients with RRP of the larynx were analyzed. The patients were treated at the University of Magdeburg between 1983 and 2014. The surgical outcomes of conventional and laser surgery regarding time to relapse and complications were compared. In addition, the influence of the quadrivalent vaccine Gardasil® on the disease was analyzed in 10 patients.

resultsChildren with RRP had a statistically significant greater number of surgeries throughout their lifetimes compared to adult patients. There were no differences between the adult (n = 79) and juvenile (n = 27) groups in the time to relapse and the number of surgeries/year. The time to relapse and number of procedures/year were not influenced by the various surgical methods. Complications after conventional and laser surgery were not statistically different between the two groups. Serious complications and the need for a tracheotomy were only reported after conventional surgery. In the 10 patients who were immunized with Gardasil®, a statistically significant lower number of surgeries/year after vaccination was achieved.

conclusionRRP is a rare disease. Treatment requires experience and may be very difficult. The analysis of the course of the disease has shown that the treatment of choice is surgical excision with the CO

Indexed as

PapillomaPapillomavirus InfectionsRespiratory Tract InfectionsAdolescentAdultAged, 80 and overChildFemaleHuman Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18HumansInfantMaleRetrospective StudiesTreatment OutcomeHuman Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18Gardasil®Human papillomavirusMicrosurgeryNeoplasms, glandular and epithelialRecurrent respiratory papillomatosis (RRP)

Identifiers

PMID28840259
OpenAlexW2746585313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.