Evidence map›Paper›PMID 28840253›Full record

ReviewCellular and molecular life sciences : CMLS2018

Interaction and cross-talk between non-coding RNAs.

Soichiro Yamamura, Mitsuho Imai-Sumida, Yuichiro Tanaka, Rajvir Dahiya

Open access · hybridAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 186 papers.

0numbers the graph read from it
0cells of the map it votes in
186citing papers in PubMed
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

186 citing papers in PubMed, 307 citations in OpenAlex.

  1. Circular RNAs in ferroptosis regulation and tumor progression of gynecological and breast cancers: molecular mechanisms and therapeutic potential.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  18. LncRNA LINC00466 Promotes the Progression of Breast CancerCurrent pharmaceutical biotechnology · 2025
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126 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Soichiro YamamuraDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA. soichiro.yamamura@ucsf.edu.ORCID 0000-0002-1660-156X
Mitsuho Imai-SumidaDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA.
Yuichiro TanakaDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA.
Rajvir DahiyaDepartment of Urology, University of California, San Francisco, San Francisco, CA, USA.
San Francisco VA Medical Center · US

Funding

MicroRNAs in the Progression and Metastisis of Prostate CancerR01CA138642 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DAHIYA, RAJVIR · 2010 to 2014
$2.6M
Chemo-dietary prevention, miRNAs, epigenetic and prostate cancerR01CA160079 · NCI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI DAHIYA, RAJVIR · 2011 to 2015
$2.2M
Genistein and chemotherapy of kidney cancerR01CA196848 · NCI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI YAMAMURA, SOICHIRO · 2016 to 2020
$1.7M
Molecular biomarkers for kidney cancer prognosis using non-coding RNAsR01CA199694 · NCI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI TANAKA, YUICHIRO · 2016 to 2020
$1.7M
Genetic factors for race related prostate cancer.U01CA184966 · NCI · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI DAHIYA, RAJVIR · 2015 to 2019
$1.6M
BLRD VA I01 BX001123BLRD VA IK6 BX004473BLRD VA IP1 BX001604NCI NIH HHS R01 CA138642NCI NIH HHS R01 CA160079NCI NIH HHS R01 CA196848NCI NIH HHS R01 CA199694NCI NIH HHS U01 CA184966NIH HHS R01CA196848NIH HHS RO1CA138642NIH HHS RO1CA160079NIH HHS RO1CA184966NIH HHS RO1CA199694VA BX001604
6 · The paper itself

Abstract

Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a competing endogenous RNAs (ceRNAs) where microRNAs (miRNAs) and lncRNAs regulate each other through their biding sites. Interactions of miRNAs and lncRNAs have been reported to trigger decay of the targeted lncRNAs and have important roles in target gene regulation. These interactions form complicated and intertwined networks. Certain lncRNAs encode miRNAs and small nucleolar RNAs (snoRNAs), and may regulate expression of these small RNAs as precursors. SnoRNAs have also been reported to be precursors for PIWI-interacting RNAs (piRNAs) and thus may regulate the piRNAs as a precursor. These miRNAs and piRNAs target messenger RNAs (mRNAs) and regulate gene expression. In this review, we will present and discuss these interactions, cross-talk, and co-regulation of ncRNAs and gene regulation due to these interactions.

Indexed as

Gene Expression RegulationGene Regulatory NetworksAnimalsEpistasis, GeneticHumansRNA, UntranslatedRNA, UntranslatedCircular RNACompeting endogenous RNAInteractionLong non-coding RNAMicroRNAPIWI-interacting RNAsSmall nucleolar RNA

Identifiers

PMID28840253
PMCPMC5765200
OpenAlexW2748715550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.